Synovis Life Technologies believes no one should have to cow to life's illnesses, no matter how serious. The company makes biomaterials (using bovine heart lining) used in surgeries to reinforce tissue and prevent air and blood leaks. Its biggest seller is the Peri-Strip buttress which is used by surgeons to reinforce surgical staple lines, mainly in gastric bypass procedures. The Veritas line of devices are used to repair soft tissue during a range of reconstructive surgeries including abdominal wall, breast, and chest wall operations. Synovis manufactures products to repair and replace damaged tissue under its Tissue-Guard brand. It also makes devices that connect vessels or nerves in microsurgery procedures.

SyntheMed helps keep surgery patients from getting scars. The company develops polymers aimed at preventing or reducing post-operative adhesions (scar tissue) for a variety of surgical procedures. In 2006 its REPEL-CV product received marketing approval from European Union regulatory authorities for prevention of scar tissue in open heart surgeries; the company launched the product in Europe and some Asian markets through a network of independent distributors. It has received approval from the FDA for use in pediatric cardiac surgery patients in the US. SyntheMed is developing similar products for use in gynecological, abdominal, orthopedic, spinal, and general surgeries.

Synthes knows that, when it comes to surgery, sometimes synthetic is superior. Synthes makes devices, instruments, and implants used for the surgical treatment of bone disease or trauma. The company also markets implant coatings, synthetic bone replacement materials, and bioresorbable implants. It specializes in spinal devices, including disc replacement and cranio-maxillofacial implants. The company also designs and manufactures the kind of surgical power tools that the squeamish would prefer not to contemplate. Synthes works closely with the AO Foundation, a not-for-profit research organization specializing in osteosynthesis. Chairman Hansjörg Wyss holds 40% of the company's shares.

Sysmex America is systematic about the analysis of the circulatory system. The company, a subsidiary of Japanese medical diagnostic equipment manufacturer Sysmex, manufactures and markets clinical laboratory testing devices and automation systems for hematology, immuno-chemistry, particle counting, and urinalysis. Subsidiary Sysmex Reagents America manufactures and distributes diagnostic reagents specifically for use in Sysmex's hematology, coagulation, and urinalysis analyzers. Its customers are pathology labs and health care providers located in the US, Canada, and Latin America; the company's products are distributed primarily through a network of independent distributors.

TechniScan (formerly TechniScan Medical Systems) is developing a gentler means of mammography. Its Svara ultrasound imaging system uses a water bath and ultrasound reflective tomography technology to produce scans of the entire breast in about 10 minutes. TechniScan's images are intended to be used when further testing is needed following a conventional mammogram screening. The development stage company was founded in 1984. TechniScan shortened its name when it completed a reverse merger with shell company Castillo Inc. to become a public entity in 2009.

Formed in 1921 to build a better thermometer, Terumo is one of Japan's largest health care product suppliers. The company makes and sells a wide range of general hospital products and equipment, including disposable supplies (syringes and wound dressings), blood glucose monitors, dialyzers, infusion pumps, and intravenous liquid nutrients. It also makes blood transfusion bags, as well as cardiac and vascular products, such as heart-lung machines used in open heart surgery, vascular grafts, and catheters. And yes, it still makes thermometers, which are part of its consumer health care product portfolio. Terumo operates in the Americas, Asia, and Europe. It sells its products in some 150 countries worldwide.

Terumo Medical Corporation (TMC) makes disposable hypodermic syringes, catheters, and blood collection and transfusion equipment, among other medical devices. TMC operates through three divisions: Terumo Interventional Systems (catheters, guidewires); Terumo Medical Products (monitors, syringes, veterinary products); and Terumo Transfusion Products (blood bags, collection equipment, transfusion sets). Along with the US, TMC has operations Brazil, Canada, and Mexico. A subsidiary of Terumo Corporation, TMC was founded in 1972.

The Medical House group of companies design, develop, and manufacture medical devices and drug delivery systems. Its Medical House Products Ltd. subsidiary manufactures drug delivery systems, such as reusable and disposable needle-free injectors and disposable do-it-yourself injectors for patients at home. Customers include pharmaceutical and biotechnology manufacturers in the UK, Europe, and the US. The company sold its Eurocut medical instrument manufacturing subsidiary to Sandvik Materials Technology in May 2008. The Medical House was founded in 1998 and went public in 2000; it has agreed to be acquired by medical device maker Consort Medical.

The SmartPill is a medical device development company that thinks small. Really small. A patient swallows a SmartPill capsule-based device which then tracks its progression through the digestive tract, including location, pressure, and the time it takes to pass through the intestines. Data measurements are transmitted via radio frequency and recorded by an external receiver for several days. Designed as a less invasive alternative to endoscopic methods that often require anesthesia, the SmartPill can help physicians diagnose and treat gastrointestinal disorders on an outpatient basis.

The Spectranetics Corporation takes its mission to heart: The company develops, markets, and distributes an excimer laser system that is used to treat various coronary and vascular conditions. Its CVX-300 laser unit and fiber-optic delivery devices (disposable catheters and sheaths) remove partial or total arterial blockages caused by plaque buildup; the laser system can also be used to remove lead wires from pacemakers and implantable defibrillators. The company's customers include major cardiac catheterization labs and hospitals in the US. Subsidiary Spectranetics International sells the company's products abroad, primarily in Europe and the Middle East.

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