Cook Incorporated makes catheters, wire guides, stents, and other devices used in minimally invasive procedures. Cook Group operates a host of other medical subsidiaries that manufacture urological and gynecological devices, endoscopic accessories, cardiac rhythm management, and vascular products. Its industrial parts manufacturer Sabin makes plastic and metal parts used in Cook's medical products, while its K-Tube company manufactures hypodermic needles. The company, one of the world's largest privately held medical device firms, was founded by William Cook in 1963.

TransMedics works to transport transplants. The company has developed a system to circulate warm blood through hearts and other transplant organs while they are being transported, as opposed to the cold transport system currently in use. The portable device makes it possible to actually deliver a beating heart to the surgeon. TransMedics' Organ Care System (OCS) is already in use in the European Union for heart transplants; it must still complete clinical trials in the US to receive FDA approval. A system for lungs, livers, and kidneys is also in the works. TransMedics was formed in 1998.

Joerns Healthcare Inc. manufactures beds, furnishings, repositioning equipment, and wound management products for the long-term care industry, including numerous hospitals and nursing homes. It has operations throughout the US, as well as in Canada, the UK, and the Netherlands, and has key partners in Australia, Germany, New Zealand, and Norway. Originally founded in 1889 as Joerns Brothers Furniture by Charles, Paul, and Frederick Joerns, the company eventually shifted its focus from high-end residential furniture to furnishings designed for the healthcare sector. In 1983 it took the Joerns Healthcare name.

Health Grades (which does business as HealthGrades) takes the health care industry to school.Health Grades company offers report cards on hospitals, physicians, nursing homes, home health agencies, and other health care providers. It sells the quality and patient safety information to a number of constituencies, including consumers, employers, and insurance companies. Hospitals themselves represent its biggest customer base, with highly rated providers typically license HealthGrades' ratings and trademarks to use in their marketing campaigns. They also come to the company for quality improvement consulting. HealthGrades was taken private by Vestar Capital Partners in 2010.

Kuakini Medical Center, a 250-bed acute care hospital that provides specialty services including cancer treatment, cardiac care, and orthopedic surgery. The hospital serves as a teaching center for the University of Hawaii's John A. Burns School of Medicine. Kuakini Health System also operates the 234-bed Kuakini Geriatric Care facility, which offers nursing home and adult day care for Honolulu's senior citizens. The system also maintains two medical office buildings. The Kuakini Health System was founded by Japanese immigrants in 1900. It is a member of the Premier group purchasing alliance.

Palomar Medical Technologies' laser light show is more functional than flashy. Palomar makes laser and pulsed-light systems, along with related disposable products, for use in aesthetic procedures. The company's products include the EsteLux, StarLux, and MediLux systems. The systems, which are paired with a variety of handpieces, are used for skin resurfacing and acne treatments, hair removal, and treatment of leg veins, among other procedures. Additionally, Palomar's Q-YAG 5 laser removes tattoos and pigmented lesions. The firm markets its products through a direct sales force and distributors around the world.

With over 100 years of industry experience, American Shared Hospital Services (ASHS) management has the talent, knowledge and infrastructure as the leading provider of radiosurgical and radiation therapy services. Our goal is to provide maximum benefit to our medical center partners with our innovative financing solutions coupled with value added services. When Tufts Medical Center in Boston was asked, “Why American Shared Hospital Services?” Denise Shepici, Senior Vice President of Clinical Services at Tufts responded, "At the time of our Gamma Knife installation, we were facing capital constraints and wanted a partner who could share the risk and help us upgrade the equipment when needed. In light of the current financial crisis, we're glad we were able to spend less upfront and still offer the technology we needed to stay competitive."

Urologix's Targis and CoolWave systems are designed to treat benign prostate hyperplasia, or enlargement of the prostate. The systems use Cooled ThermoTherapy, a noninvasive catheter-based therapy that applies microwave heat to the diseased areas of the prostate, while cooling and protecting urethral tissue. The treatment, an alternative to drug therapy, does not require anesthesia or surgery and can be administered on an outpatient basis. Urologix markets its products through a direct sales force in the US, as well as through international distributors.

Owen Mumford products include a variety of injection-based drug delivery systems, blood sampling equipment, neuropathy testers, and sexual healthcare devices. The company's Autopen line of insulin injectors use a side-mounted slide instead of a plunger, which is part of a design that is meant to minimize pressure and bruising. The company also makes Unilet lancets in a number of sizes for use in blood sampling and testing. Owen Mumford offers custom design services as well. The company was started in 1952 by Ivan Owen and John Mumford, originally making products for the auto industry.

Excela Health's hospitals and clinics hope to rank as excellent health care providers to residents of southwestern Pennsylvania. Members of the health system, which serves Pennsylvania's Westmoreland, Indiana, and Fayette counties, include Westmoreland Hospital, Latrobe Hospital, and Frick Hospital. Combined, the facilities give Excela Health some 615 acute care beds. In addition to general medical and surgical care, the hospitals offer outpatient and specialty treatment in areas such as heart disease, cancer, and women's health. The system operates ancillary businesses as well, including a home health and hospice agency, surgery centers, primary and specialty care clinics, and an ambulance service.

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