Integtra Radionics designs and produces medical devices for neurosurgery and radiation therapy. Its products include non-invasive radiosurgical systems, stereotactic surgery systems which facilitate the placement of instruments on the brain during neurosurgery, aspirators used in ultrasonic surgical procedures, and extracranial systems to hold patients in place during surgery. Formerly a division of Covidien, Integra Radionics was acquired by Integra LifeSciences Holdings in 2006. The wholly-owned subsidiary fortifies Integra's radiosurgery/radiotherapy and image-guided surgery devices business.

Home Instead has a network of some 900 franchises operating throughout the US and in more than a dozen countries internationally. Employees known as CAREGivers provide the elderly with one-on-one assistance in the home and at assisted living or nursing care facilities. Home Instead helps keep the elderly at home instead of in assisted living or nursing homes. The company -- operating under the name Home Instead Senior Care -- provides non-medical home care assistance for seniors. Its services are designed for people who are capable of managing their physical needs but require assistance, supervision, light housework, meals, errands, or simply companionship in order to remain in their homes.

Brooks Health System operates Brooks Rehabilitation Hospital, a more than 140-bed facility dedicated to helping patients recover from injury and illness. Rehabilitation services include physical, occupational, and speech therapy. The not-for-profit hospital also helps patients coping with chronic pain, cognitive disorders, and other long-term disabilities. Brooks Health System provides outpatient care through a network of some two dozen outpatient clinics in northeast Florida. The system is a research affiliate of the Health Science Center at the University of Florida.

CCS Medical Holdings, Inc. emerged from Chapter 11 bankruptcy protection in 2010. CCS Medical Holdings knows that doorstep delivery is just a convenience for many, but it's critical for patients with chronic conditions. The company provides mail-order delivery of medical supplies to treat diabetes, as well as chronic wounds, incontinence, respiratory ailments, and other illnesses. CCS distributes a variety of drugs and medical supplies including blood glucose meters, catheters, insulin pumps, nebulizers, and ostomy and wound care supplies. It is one of the largest providers of respiratory medications and diabetes testing supplies to Medicare customers.

University Health System serves the residents (and rebels) of San Antonio and the surrounding region. Its flagship facility, University Hospital, has about 500 beds and is the primary teaching facility for The University of Texas Health Science Center at San Antonio. In addition to general medical and surgical care, the hospital is a designated Level 1 trauma center and offers care in a wide range of medical specialties. University Health System includes a network of primary and specialty care clinics.

Weirton Medical Center has 240-bed, not-for-profit hospital provides a wide range of health services to the tri-state region of West Virginia, Ohio, and Pennsylvania. Inpatient services include pediatrics, obstetrics, and other acute care services. Founded in 1953, the hospital also offers clinical and diagnostic care services such as emergency medicine, home health care, rehabilitation, and occupational therapy. Weirton Medical Center has seen a steady decrease in patient volumes in recent years forcing the hospital to enact a number of cost-saving measures including cutting back on some services and laying off employees.

The Lytles founded Leisure Care in 1976 and still own most of its real estate. Leisure Care provides upscale independent and assisted-living rental housing to people age 62 or older. Leisure Care takes the leisure part of its name seriously, offering residents access to vacation tour packages through its Twist Travel unit and full-services concierge and valet services at its more than 40 communities throughout the western US and Canada. President and CEO Dan Madsen bought Leisure Care, LLC from Chuck and Karen Lytle, its original owners, in 2003.

HemCon Medical Technologies has been a boon to US soldiers wounded on the battlefield. The company's proprietary HemCon bandages and ChitoFlex dressings stop bleeding in trauma patients; in fact, the dressing becomes adhesive upon contact with blood and can prevent hemorrhage. HemCon bandages are made from chitosan, a polysaccharide derived from dried shrimp shells and known for its clotting abilities. Besides the military, its products are used by first responders, oral surgeons, and hospitals. The company was founded in 2001 with partial funding from the US Army; HemCon bandages are now part of every Army medic's standard kit.

Kips Bay Medical makes medical devices that help veins do their jobs in patients with coronary artery disease. The development-stage company is focused on developing and commercializing a vein support device called eSVS MESH, a mesh sleeve implanted by surgeons in coronary artery bypass grafting (CABG) that, when placed over a patient's vein graft, improves the graft's structure and long-term performance. It is designed to mimic the artery's job of constricting the vein and preventing harmful vessel expansion. The company is conducting clinical trials of its eSVS MESH in Europe and is awaiting approval to begin clinical trials in the US. Kips Bay Medical filed a $57.5 million IPO in April 2010.

Akers Biosciences,Inc. manufactures a variety of point-of-care rapid diagnostic tests. In addition to tests for such diseases as malaria, it has produced screening tools to detect drug and enzyme levels in blood. ABI has also developed sniffing devices to detect breath alcohol as well as diseases such as lung disease and diabetes through breath analysis. Another product whiffs for biological warfare agents in the air. Its Tri-Cholesterol product is a home-use test kit. ABI customers include healthcare facilities (hospitals, physicians' offices) as well as the US military and aid organizations.

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