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SyntheMed helps keep surgery patients from getting scars. The company develops polymers aimed at preventing or reducing post-operative adhesions (scar tissue) for a variety of surgical procedures. In 2006 its REPEL-CV product received marketing approval from European Union regulatory authorities for prevention of scar tissue in open heart surgeries; the company launched the product in Europe and some Asian markets through a network of independent distributors. It has received approval from the FDA for use in pediatric cardiac surgery patients in the US. SyntheMed is developing similar products for use in gynecological, abdominal, orthopedic, spinal, and general surgeries.

Synthes knows that, when it comes to surgery, sometimes synthetic is superior. Synthes makes devices, instruments, and implants used for the surgical treatment of bone disease or trauma. The company also markets implant coatings, synthetic bone replacement materials, and bioresorbable implants. It specializes in spinal devices, including disc replacement and cranio-maxillofacial implants. The company also designs and manufactures the kind of surgical power tools that the squeamish would prefer not to contemplate. Synthes works closely with the AO Foundation, a not-for-profit research organization specializing in osteosynthesis. Chairman Hansjörg Wyss holds 40% of the company's shares.

Sysmex America is systematic about the analysis of the circulatory system. The company, a subsidiary of Japanese medical diagnostic equipment manufacturer Sysmex, manufactures and markets clinical laboratory testing devices and automation systems for hematology, immuno-chemistry, particle counting, and urinalysis. Subsidiary Sysmex Reagents America manufactures and distributes diagnostic reagents specifically for use in Sysmex's hematology, coagulation, and urinalysis analyzers. Its customers are pathology labs and health care providers located in the US, Canada, and Latin America; the company's products are distributed primarily through a network of independent distributors.

TechniScan (formerly TechniScan Medical Systems) is developing a gentler means of mammography. Its Svara ultrasound imaging system uses a water bath and ultrasound reflective tomography technology to produce scans of the entire breast in about 10 minutes. TechniScan's images are intended to be used when further testing is needed following a conventional mammogram screening. The development stage company was founded in 1984. TechniScan shortened its name when it completed a reverse merger with shell company Castillo Inc. to become a public entity in 2009.

Formed in 1921 to build a better thermometer, Terumo is one of Japan's largest health care product suppliers. The company makes and sells a wide range of general hospital products and equipment, including disposable supplies (syringes and wound dressings), blood glucose monitors, dialyzers, infusion pumps, and intravenous liquid nutrients. It also makes blood transfusion bags, as well as cardiac and vascular products, such as heart-lung machines used in open heart surgery, vascular grafts, and catheters. And yes, it still makes thermometers, which are part of its consumer health care product portfolio. Terumo operates in the Americas, Asia, and Europe. It sells its products in some 150 countries worldwide.

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