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Terumo Medical Corporation (TMC) makes disposable hypodermic syringes, catheters, and blood collection and transfusion equipment, among other medical devices. TMC operates through three divisions: Terumo Interventional Systems (catheters, guidewires); Terumo Medical Products (monitors, syringes, veterinary products); and Terumo Transfusion Products (blood bags, collection equipment, transfusion sets). Along with the US, TMC has operations Brazil, Canada, and Mexico. A subsidiary of Terumo Corporation, TMC was founded in 1972.

The Medical House group of companies design, develop, and manufacture medical devices and drug delivery systems. Its Medical House Products Ltd. subsidiary manufactures drug delivery systems, such as reusable and disposable needle-free injectors and disposable do-it-yourself injectors for patients at home. Customers include pharmaceutical and biotechnology manufacturers in the UK, Europe, and the US. The company sold its Eurocut medical instrument manufacturing subsidiary to Sandvik Materials Technology in May 2008. The Medical House was founded in 1998 and went public in 2000; it has agreed to be acquired by medical device maker Consort Medical.

The SmartPill is a medical device development company that thinks small. Really small. A patient swallows a SmartPill capsule-based device which then tracks its progression through the digestive tract, including location, pressure, and the time it takes to pass through the intestines. Data measurements are transmitted via radio frequency and recorded by an external receiver for several days. Designed as a less invasive alternative to endoscopic methods that often require anesthesia, the SmartPill can help physicians diagnose and treat gastrointestinal disorders on an outpatient basis.

The Spectranetics Corporation takes its mission to heart: The company develops, markets, and distributes an excimer laser system that is used to treat various coronary and vascular conditions. Its CVX-300 laser unit and fiber-optic delivery devices (disposable catheters and sheaths) remove partial or total arterial blockages caused by plaque buildup; the laser system can also be used to remove lead wires from pacemakers and implantable defibrillators. The company's customers include major cardiac catheterization labs and hospitals in the US. Subsidiary Spectranetics International sells the company's products abroad, primarily in Europe and the Middle East.

Theragenics' seeds, sold under the names TheraSeed and I-Seed, are tiny rice-sized radioactive implants used to fight prostate cancer. The devices (known more generally as brachytherapy seeds) are a common treatment for early-stage prostate cancer; they release radiation within the tumor that kills cancerous cells with minimal damage to surrounding healthy tissue. Theragenics sells the devices directly to hospitals and through distribution agreements throughout the US and in Europe. In addition to its brachytherapy business, Theragenics' surgical products unit makes vascular and wound care products, including sutures and guidewires.

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