Positron Corporation makes positron emission tomography (PET) scanners under the POSICAM and mPower trade names. The scanners are primarily used to detect coronary artery disease but also have applications in neurology and oncology. Medical centers such as the University of Texas Health Science Center at Houston and the Heart Center of Niagara use the system; the company has an installed base of about 30 systems in the US and abroad. Subsidiary IS2 Medical Systems (acquired in 2006) makes nuclear imaging devices, including the PulseCDC cardiac gamma camera.

Precision Optics makes specialized video cameras and stereo endoscopes for use in minimally invasive surgery. Its other products include laparoscopes (for abdominal surgery) and arthroscopes (for joint surgery), as well as sterilizable image couplers and beamsplitters that connect endoscopes to video cameras. The US is Precision Optics' biggest market, accounting for almost all sales, although the company has received regulatory approval to sell its products in Europe. In 2008 the company sold it custom optical thin film coatings business to privately held Optometrics, a subsidiary of Dynasil.

Pride Mobility Products makes motorized wheelchairs and scooters for elderly and disabled users. Its electric wheelchairs go by the names Jazzy, Jet, and Quantum Rehab, and scooters are sold under the Pride and Go-Go brands. Pride Mobility's Silver Star division makes automobile lifts, used to transfer a chair or scooter into the car. The company also makes chair lifts (assisting users in getting up from a sitting position), as well as manual wheelchairs. Founded in 1986, Pride Mobility is owned by the Meuser family. Scott Meuser is Pride's CEO and chairman of the board.

PRIM started its business on more than just a shoestring. Tracing its roots to an orthopedic shoe store founded by Pedro Prim Fernández in 1870, PRIM now makes and markets hospital supplies in Spain and orthopedic supplies throughout Europe, Latin America, and the US. PRIM has expanded globally through several alliances: It works in the US with Camp International and it operates a joint venture with Enraf Nonius Delft in Portugal and Latin America, as well as domestically. In France PRIM works with Eurosurgical to develop items to aid surgery of the spine. With another three European prosthetic companies, PRIM owns 92% of Boston Brace Europe, an Irish company that makes aids for the treatment of scoliosis.

Progressive Medical hopes its pressure therapy will make progress in getting rid of bed sores. The company sells a variety of therapeutic air and foam mattresses and related medical products to patients with wound care needs, pulmonary complications, and immobility (i.e. paraplegics and quadriplegics). Its mattresses help to prevent and also heal patients' bedsores. The company's other products include negative pressure (vacuum) wound therapy systems and durable medical equipment (wheelchairs, walkers, and commodes), as well as products for bariatric patients. Progressive Medical also provides consulting and condition assessment services.

Pyng Medical (formerly Pyng Technologies) makes an intraosseous infusion device called FAST1 (First Access for Shock and Treatment) that hydrates victims of rapid blood loss or vein collapse -- usually the result of cardiac arrest or severe trauma. The device is used by emergency medical personnel, including those in the military (specifically, the US Department of Defense), which accounts for nearly half of Pyng Medical's total units shipped. The company sells its devices in North America, Europe, and Asia.

Q-Med seeks a smooth future, but thus far it still has a few wrinkles in its plans. The company develops and manufactures the high-tech goo Restylane dermatologists inject to fill in lines and creases in facial skin. Its Durolane product, also based on its non-animal sourced hyaluronic acids, is used as an injection to treat osteoarthritis of the knee. Its products are distributed in over 70 countries, but only Restylane has received FDA approval for use in the US. The Swedish company entered the US exchanges by buying up the shell of a public company in 2008.

Refocus Group is a medical device company that develops surgical treatments for human vision disorders. Therapeutic targets include presbyopia (commonly known as farsightedness), elevated blood pressure in the eye, and a certain form of glaucoma. Its most advanced device is the Scleral Spacing Procedure, which includes an incision handpiece, implants, and related surgical equipment, that could treat the previously mentioned vision disorders. Medcare Investment owns more than half of the firm.

ReGen Biologics, Inc. makes tissue implants and medical devices that are used to repair damaged or degenerating cartilage. ReGen's product line focuses on the repair and preservation of the meniscus, a piece of cartilage found in the knees. The company makes Menaflex, a collagen matrix product designed to halt deterioration, support natural regrowth of tissue, restore function, and reduce pain; the implant is approved for sale in Europe and the US (though its approval is under review in the US market). ReGen also makes the SharpShooter Tissue Repair System, a suturing device used in the Menaflex implantation procedure.

ResMed makes and distributes medical equipment used to diagnose and treat respiratory disorders that occur during sleep, such as sleep apnea. Most of its products treat obstructive sleep apnea (OSA), a condition in which a patient's air flow is periodically obstructed, causing multiple disruptions during sleep that lead to daytime sleepiness and possibly other conditions such as high blood pressure. Its products include air-flow generators, face masks, diagnostic products, and accessories. ResMed sells directly and through distributors worldwide to home health equipment dealers, sleep clinics, and hospitals.

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