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REVA Medical Inc., founded in 1998, makes thin-walled heart and coronary artery stents from "bioresorbable" polymer materials using a "slide and lock" stent design. Its lead product candidate is the ReZolve coronary stent designed to restore blood flow and then resorb into the vessel. The company's products could also have applications in the orthopedic, neurological, and peripheral stent markets. Leading cardiac device maker Boston Scientific has partnered with REVA Medical and is helping the company develop its stents. The collaboration agreement also gives Boston Scientific the option to exclusively distribute REVA Medical's products if commercialized.

Robert Bosch Healthcare (formerly Health Hero Network) wants to be your healthy buddy. The subsidiary of Robert Bosch makes the Health Buddy brand of patient monitoring systems and other means of keeping patients and doctors connected. Health care providers use the systems to communicate with patients, collect vital health information, and provide feedback to patients on health progress. Using the system, diabetics can monitor their blood glucose level or be reminded to take their medicine. The company sells the Health Buddy systems to hospitals and HMOs; drug developers use the product for assistance in clinical trials.

Rockwell Medical Technologies keeps on trucking with its hemodialysis products. The company (which does business as Rockwell Medical) makes hemodialysis concentrates (in liquid and dry powder form), dialysis kits, and other related products for treatment of end-stage renal disease (chronic kidney failure). Subsidiary Rockwell Transportation delivers supplies to its customers in 35 US states via its own truck fleet. The company markets and distributes its products directly to hemodialysis providers across the US, as well as through independent distributors abroad (primarily in Asia, Europe, and Latin America).

When it comes to surgical implants, RTI Biologics recommends the natural alternative. The firm develops products made from human and animal tissue that are used in orthopedic, dental, and other surgeries to repair fractures, spinal disorders, sports injuries, breast reconstruction, and other procedures. Using its BioCleanse and Tutoplast processes, the company sterilizes tissue -- including bone, tendons, and skin -- that is then used in surgeries. RTI Biologics sells its allografts (made from human tissue) and xenografts (made from animals) in the US and more than 30 countries. Its direct sales force targets the sports medicine and general orthopedic markets.

Safety Syringes wants to ensure that when you're getting needled, it's with deliberate intention. The company manufactures devices designed to prevent accidental needle pricks. Safety Syringe's products include UltraSafe Needle Guards, which attach to prefilled glass syringes, and UltraSafe Passive Needle Guards, in which a safety guard locks into place upon completion of shot delivery. The company develops products used for medical and dental drug delivery, vaccines, blood collection, and intravenous catheters. Customers for pre-filled syringes include Amgen, Merck, Roche, and Pfizer. The company was founded in 1990 and primarily operates in North America, Europe, and Asia.

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