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Noninvasive Medical Technologies helps physicians provide gentler health care. The company manufactures noninvasive hemodynamic monitors that measure blood flow, heart rate, stroke volume, and cardiac output. Its IQ2 is used to assess and evaluate cardiac function. The ZOE device determines if a patient is retaining fluids or is dehydrated without drawing blood. By quickly assessing fluid status, doctors can better treat those at risk for severe or recurring dehydration such as hypertension and heart failure patients and athletes. The company also sells ICG sensors (to obtain hemodynamic data) and electrodes used with its devices. NMT has a supplier agreement with Royal Philips Electronic for its ZOE monitor.

Novadaq Technologies produces medical imaging devices that are used during surgeries. Its SPY Intra-Operative Imaging System uses the fluorescent properties of indocyanine green dye to give surgeons new views of the arteries and grafts they're working on during coronary or reconstruction surgery. The company's PINPOINT imaging system is used to identify healthy and cancerous tissues during lung surgeries. Novadaq is also developing the OPTTX System to diagnose and treat age-related macular degeneration (AMD) -- it combines two functions, imaging and cauterizing, into one device.

NxStage Medical is giving some life back to those needing dialysis to treat acute kidney failure and end-stage renal disease. The medical device company's primary product, System One, is a portable hemodialysis machine, which can be used by patients at home or by professionals in a hospital setting. The FDA-approved device is also marketed to hospitals for critical care and to dialysis clinics that want to create or expand their services to home-based patients. Typically, customers rent the System One equipment, but its largest customer, DaVita, has chosen to purchase. NxStage Medical's subsidiary, Medisystems, supplies customers with disposable blood tubing and needles.

Oncology Services International (OSI) sells, installs, and provides radiation therapy equipment and related services, including medical linear accelerators, GE Computed Tomographic Scanners, radiation therapy simulators, and accessories worldwide. The company was formed following the merger between Accelinear and Linac Systems in 2003. OSI has facilities in California, Georgia, New Jersey, Ohio, and Texas.

Optos has opted to provide improved imaging tools to eye doctors. The company is a manufacturer of digital diagnostic imaging equipment used by ophthalmologists and other eye care professionals in the detection and management of eye disease. The company's Optomap laser ophthalmoscopes are used by ophthalmologists to perform precision retinal examinations. Its tools are used to detect ailments such as retinal detachments, age-related macular degeneration, and glaucoma and are marketed to physicians in Europe and North America. Optos was founded in 1992 by executive vice chairman and engineer Douglas Anderson after his son's retinal disorder was overlooked by eye doctors.

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