Sopheon sells product lifecycle management (PLM) software, primarily to companies with a heavy emphasis on research and development. Its flagship product, Accolade, is a software application used to manage process and product development, and Vision Strategist is its product planning software. Sopheon also makes products to manage protocols and compliance regulations. Its 135 licensed clients come from the automotive, high-tech manufacturing, chemical, food and beverage, and healthcare industries and include General Motors, GlaxoSmithKline, Glatfelter, Cargill, Land O'Lakes, and Sanofi-Aventis. Chairman Barry Mence controls about 10% of the company's stock.

Source Software was founded in 1993. Source Software provides comparative quotation sourcing software for the mortgage, insurance, and assurance markets. Source Software's software includes applications for homeowners', life, accident, rental, travel, and unemployment insurance, as well as mortgage lending. Source Software's Internet-based software handles online comparative quotes, confirmation of coverage, and sales support. The system also generates application and related payments documentation for represented policies.

Launched in late 2001 in Seattle Washington, Spam Arrest's patent-protected and affordable system efficiently stops spam while offering extensive user flexibility. Utilizing the challenge-response system, the only system which blocks 100% of automated junk email, Spam Arrest can be configured to work with your current email program, or you can manage all your email online through your Spam Arrest account.In just a few short years, Spam Arrest has seen explosive growth in its user base while steadily expanding services and increasing functionality. Considered by many to be the top spam blocking service around, Spam Arrest prides itself on its continued efforts at monitoring automated junk email techniques, upgrading automatically as necessary to protect its users from viruses, phishing and unwanted email.

Spanlink Communications, Inc. was founded in 1988 by former CEO Brett Shockley and other investors. Spanlink Communications provides call center agents and administrators with information management software and systems to process customers and route calls efficiently. It also offers applications for automated, self-service customer assistance, as well as Web conferencing systems for conducting meetings and presentations. Most of the company's software is built on Cisco System's technologies as part of a reseller partnership agreement. In addition to software, Spanlink also provides consulting, training, support, and systems integration services.

Founded in 1994, Sparta Systems provides software that logs and tracks quality assurance and compliance issues and the efforts organizations take to correct them. Its flagship TrackWise software includes tools for tracking deviations, complaints, audits, and changes. With its focus on industries regulated by the Food and Drug Administration, Sparta has a significant customer base in the biotech and pharmaceutical industries, including Biogen Idec and GlaxoSmithKline. Other customers include manufacturers like Briggs & Stratton and Texas Instruments, and government clients such as the California Public Employees' Retirement System (CalPERS) and NASA.

Spectrum Human Resource Systems Corporation was founded in 1984. Spectrum Human Resource Systems sells software that helps businesses manage their human resources tasks more effectively. Its iVantage software is a Web-based human resources information system that automates administrative tasks, tracks workforce metrics, and allows employees and managers to access information. The company also sells a similar product for small and midsized companies called HRVantage, which operates on the client's local-area network. Spectrum sells its products as licensed software or as a hosted service. It also provides in-house support services for its software, including installation, training, and hotline support.

Spotfire makes software for analyzing business processes, transforming complex data into images that reveal the relationships between pieces of information. Its Spotfire DecisionSite analytics software provides a data analysis environment that enables users to visually manipulate data and to automatically capture and annotate their analysis work. Spotfire also offer installation, training workshops, and technical support. Spotfire's customers come from the life sciences, energy, manufacturing, and academic research markets and include Chevron, SAAB, Eli Lilly and Harvard University. Spotfire was acquired by TIBCO Software in 2007.

SPS Commerce provides the means for business communication. Sharing vital information over the company's primary software platform, SPCCommerce.net, grocery chains, retailers, large distributors, and factories use SPC Commerce's Web-based software to place and fill orders and track the shipments of goods. On top of this network, SPS Commerce has built services tailored to fit the many ways companies interact with vendors and clients. SPS Commerce has more than 35,000 customers in 26 countries. Among them are Best Buy, Costco, Rite Aid, and Sears.

SPSS's predictive analytics software performs such functions as statistical analysis, data mining, performance measurement, and fraud detection. Its business intelligence products measure and predict customer behavior in such areas as sales and targeted marketing. The data can then be stored, further analyzed, and distributed or used to generate reports. SPSS' data mining tools offer language-based search and categorization tools. Customers include research analysts, financial services firms, telecommunications companies, government agencies, and educational institutions. In 2009 the company was acquired by IBM for about $1.2 billion.

SS&C Technologies Holdings, Inc. designs software for managing financial portfolios, loans, real estate equity, back-office processing, and securities trading, and it provides consulting and outsourcing services. SS&C's software handles investment portfolio management, asset and liability management for actuaries, property and casualty insurance risk management, trade ordering, and financial modeling. Customers include asset managers, insurance companies, banks, corporate treasuries, hedge funds, and government agencies. SS&C Technologies gets about three-quarters of its revenues in North America. The Carlyle Group is the majority shareholder of SS&C Technologies.

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