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Founded in 1994, Sparta Systems provides software that logs and tracks quality assurance and compliance issues and the efforts organizations take to correct them. Its flagship TrackWise software includes tools for tracking deviations, complaints, audits, and changes. With its focus on industries regulated by the Food and Drug Administration, Sparta has a significant customer base in the biotech and pharmaceutical industries, including Biogen Idec and GlaxoSmithKline. Other customers include manufacturers like Briggs & Stratton and Texas Instruments, and government clients such as the California Public Employees' Retirement System (CalPERS) and NASA.

Spectrum Human Resource Systems Corporation was founded in 1984. Spectrum Human Resource Systems sells software that helps businesses manage their human resources tasks more effectively. Its iVantage software is a Web-based human resources information system that automates administrative tasks, tracks workforce metrics, and allows employees and managers to access information. The company also sells a similar product for small and midsized companies called HRVantage, which operates on the client's local-area network. Spectrum sells its products as licensed software or as a hosted service. It also provides in-house support services for its software, including installation, training, and hotline support.

Spotfire makes software for analyzing business processes, transforming complex data into images that reveal the relationships between pieces of information. Its Spotfire DecisionSite analytics software provides a data analysis environment that enables users to visually manipulate data and to automatically capture and annotate their analysis work. Spotfire also offer installation, training workshops, and technical support. Spotfire's customers come from the life sciences, energy, manufacturing, and academic research markets and include Chevron, SAAB, Eli Lilly and Harvard University. Spotfire was acquired by TIBCO Software in 2007.

SPS Commerce provides the means for business communication. Sharing vital information over the company's primary software platform, SPCCommerce.net, grocery chains, retailers, large distributors, and factories use SPC Commerce's Web-based software to place and fill orders and track the shipments of goods. On top of this network, SPS Commerce has built services tailored to fit the many ways companies interact with vendors and clients. SPS Commerce has more than 35,000 customers in 26 countries. Among them are Best Buy, Costco, Rite Aid, and Sears.

SPSS's predictive analytics software performs such functions as statistical analysis, data mining, performance measurement, and fraud detection. Its business intelligence products measure and predict customer behavior in such areas as sales and targeted marketing. The data can then be stored, further analyzed, and distributed or used to generate reports. SPSS' data mining tools offer language-based search and categorization tools. Customers include research analysts, financial services firms, telecommunications companies, government agencies, and educational institutions. In 2009 the company was acquired by IBM for about $1.2 billion.

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