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St. Lucie Medical Center, part of the HCA network of health care providers, is an acute-care hospital serving the Port St. Lucie community in Florida's Treasure Coast region. The hospital has about 200 beds and 250 physicians on staff. Specialty programs and services include cancer care, women's care, orthopedics, physical rehabilitation, and outpatient surgery services. St. Lucie Medical Center, founded in 1983, is part of the HCA East Florida division. Affiliate Integrated Regional Laboratories provides medical testing services for St. Lucie and other area hospitals.

St. Luke's Episcopal Health System cares for Lone Star Staters through flagship St. Luke's Episcopal Hospital, which performed the first heart transplant in the US. St. Luke's Episcopal Health System also operates smaller area hospitals, the Texas Heart Institute, a network of community clinics, and other specialized services in and around Houston. Founded in 1954, the system has some 950 beds and a medical staff of more than 600 doctors. The company's physicians provide more than 20 clinical services in more than 40 specialties.

St. Luke's Health System strives to live up to its namesake. The regional not-for-profit health system provides a range of health services to residents of Idaho, eastern Oregon, and northern Nevada. St. Luke's is home to four general acute care hospitals with a total of about 800 beds. Its flagship facility is the 400-bed St. Luke's Boise Regional Medical Center, which also includes a full-service children's hospital. St. Luke's also runs a network of cancer care sites under the name Mountain States Tumor Institute, as well as diagnostic imaging and breast cancer detection centers.

St. Luke's Hospital & Health Network serves Pennsylvania's Greater Lehigh Valley. The health care network includes four tertiary and acute care hospitals: St. Luke's Hospital of Bethlehem, St. Luke's Hospital - Allentown, St. Luke's Quakertown Hospital, and St. Luke's Miners Memorial Hospital. The health system has about 750 beds total. Other operations include outpatient and urgent care facilities, rehabilitation and surgery centers, nursing homes, and home health and hospice services. St. Luke's Hospital & Health Network has cooperative agreements with the University of Pennsylvania Health System and St. Christopher's Hospital for Children to provide expanded care in its communities.

St. Luke's Hospital - Allentown Campus specializes in acute care and family health services. The hospital, which has some 140 beds, is part of St. Luke's Hospital & Health Network. Among the Allentown hospital's specialty services are cardiology, emergency care, obstetrics, podiatry, occupational medicine, and pediatrics. The facility has specialty centers for cancer treatment, sleep disorders, imaging, and weight loss surgery. It also offers free health screenings to the community and works with a weekly school-based health center at a local middle school. St. Luke's Hospital - Allentown Campus traces its roots to the 1945 founding of the Allentown Osteopathic Medical Center.

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