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World Heart develops VADs (ventricular assist devices) that can be implanted within the chest cavity next to the natural heart. Through the transcutaneous energy and information transfer (TEIT) system, electric power is used to monitor and control the heart. The devices are used as a bridging device for patients awaiting a transplant and for long-term support. World Heart's main product is the Novacor LVAS. The company has facilities in the US, the Netherlands, and Canada. World Heart is developing next-generation VAD products.

Wright Medical Group wants to make your knees and hips work all right. The company makes reconstructive implants for knees, hips, and other joints. Product lines include the ADVANCE knee system, CONSERVE and PERFECTA hip systems, the OLYMPIA shoulder and trauma system, and Swanson finger and wrist implants. Wright Medical also makes an injectable putty for bone defects as well as bone graft and tissue substitute materials such as OSTEOSET pellets used to regenerate bone. Wright Medical sells its products in more than 60 countries through distributors and a direct sales force that targets customers in the orthopedic surgery market.

Xograph Healthcare is a specialist company that sells medical-imaging equipment to health care providers involved in general diagnostic radiology, mammography, and mobile imaging. In addition to X-ray equipment manufactured by other companies, Xograph designs and manufactures quality control instruments for X-ray equipment. The company provides technical support for its equipment. Sales efforts focus on hospitals (NHS, private, and military) and veterinary clinics in the UK and Ireland. Other clients include chiropractors, research labs, and industrial users. Xograph sells its products in more than 35 countries.

Z-Medica manufactures and sells QuickClot, a product that rapidly stops bleeding in emergency situations, even from arterial injuries. QuickClot works by absorbing blood plasma, the liquid component of blood, and thereby concentrating clotting factors. The hemostat is made of biologically inert minerals, reducing the risk of a patient having an allergic reaction to the compound. QuickClot has been used by the US armed forces in Iraq and is available to civilian medical, emergency, and veterinary customers, as well as over-the-counter to the general public. Z-Medica, founded in 2002, also makes the product available to international buyers through distributors.

Zila is developing and commercializing oral cancer detection technology, as well as equipment used to prevent and treat periodontal disease. Its lead cancer diagnostic product is the ViziLite Plus test kit, which uses a chemiluminescent light source to detect cancerous oral lesions. Despite its FDA approval as an adjunctive diagnostic (to be used along with other methods), the ViziLite has yet to fully take off in the US. Other products include the periodontal scalers, probes, fluoride rinses, and cleaning equipment for office and home use. After experiencing financial difficulties, Zila was acquired by private drugmaker TOLMAR Holding in 2009.

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