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PhotoMedex manufactures and markets dermatological treatments for skin disorders such as acne, psoriasis, and vitiligo (loss of skin pigmentation). Other products include gels and creams intended to promote skin rejuvenation and hair growth. PhotoMedex also develops lasers and fiber-optic equipment for dermatological and surgical applications. Its FDA-approved XTRAC excimer laser system is used for the treatment of psoriasis and eczema. The company operates throughout the US and internationally serving dermatologists, cosmetic surgeons, and spas.

Physio-Control (formerly Medtronic Emergency Response Systems) makes an integrated line of noninvasive emergency cardiac defibrillators and vital-sign assessment devices, as well as data management software. The company's LIFEPAK branded products are used both in and outside hospitals for the early detection and treatment of life-threatening events including trauma, heart attack, and the acute heart rhythm disturbances of bradycardia (slow heartbeat), tachycardia (rapid heartbeat), and ventricular fibrillation (chaotic heartbeat). Physio-Control is a unit of medical device maker Medtronic.

PLC Systems guards kidneys against ill effects of dehydration and toxic medicines. Its RenalGuard system, marketed in Europe, is a fluid balancing device that helps physicians monitor and maintain kidney fluid levels during medical imaging procedures. The company also developed the Heart Laser System, a carbon dioxide laser system that treats coronary artery disease; the system performs Transmyocardial Revascularization (or TMR) as an alternative to such conventional therapies as bypass surgery and balloon angioplasty. Novadaq is PLC Systems' exclusive distributor for its TMR business in the US; PLC agreed to sell the TMR business to Novadaq in 2010 to focus on development of RenalGuard for the US market.

Positron Corporation makes positron emission tomography (PET) scanners under the POSICAM and mPower trade names. The scanners are primarily used to detect coronary artery disease but also have applications in neurology and oncology. Medical centers such as the University of Texas Health Science Center at Houston and the Heart Center of Niagara use the system; the company has an installed base of about 30 systems in the US and abroad. Subsidiary IS2 Medical Systems (acquired in 2006) makes nuclear imaging devices, including the PulseCDC cardiac gamma camera.

Precision Optics makes specialized video cameras and stereo endoscopes for use in minimally invasive surgery. Its other products include laparoscopes (for abdominal surgery) and arthroscopes (for joint surgery), as well as sterilizable image couplers and beamsplitters that connect endoscopes to video cameras. The US is Precision Optics' biggest market, accounting for almost all sales, although the company has received regulatory approval to sell its products in Europe. In 2008 the company sold it custom optical thin film coatings business to privately held Optometrics, a subsidiary of Dynasil.

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