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A breast biopsy is not the most pleasant prospect for any woman, but Intact Medical would like to make the experience a little less arduous and invasive. The company's Intact Breast Lesion Excision System needs just ten seconds to retrieve a tissue sample using vacuum technology and a single needle. It also keeps a the sample intact (thus the name) for easier diagnosis. Intact Medical was established in 1998, and the system received FDA approval in 2001. The Intact system has since been expanded for additional use including removing benign lesions, and the company has produced improved versions of the product.

Integtra Radionics designs and produces medical devices for neurosurgery and radiation therapy. Its products include non-invasive radiosurgical systems, stereotactic surgery systems which facilitate the placement of instruments on the brain during neurosurgery, aspirators used in ultrasonic surgical procedures, and extracranial systems to hold patients in place during surgery. Formerly a division of Covidien, Integra Radionics was acquired by Integra LifeSciences Holdings in 2006. The wholly-owned subsidiary fortifies Integra's radiosurgery/radiotherapy and image-guided surgery devices business.

Interpore Spine has biomaterials deep in its bones. The company, which operates as Interpore Cross, makes synthetic tissue, bone products, and implant systems for spinal and orthopedic procedures. Interpore also makes biological grafting products that encourage bone growth. Interpore Spine also manufactures minimally invasive surgery systems used by orthopedic surgeons and neurologists. Brands include Pro Osteon, InterGro, and BioPlex. The company is a subsidiary of Biomet; other sister company products include dental implants, sports medicine devices, and bracing equipment.

Intuitive Surgical is haptic to meet you. Employing haptics (the science of computer-aided touch sensitivity), the firm has developed the da Vinci Surgical System, a combination of software, hardware, and optics that allows doctors to perform robotically aided surgery from a remote console. The da Vinci system reproduces the doctor's hand movements in real time, with surgery performed by tiny electromechanical arms and instruments inserted in the patient's body through small incisions. The company also makes the instruments and accessories used with its system. Intuitive Surgical sells its products in the Americas, Asia, Australia, and Europe through both a direct sales force and independent distributors.

Invacare allows wheelchair users to set their own pace. Invacare is a leading maker of wheelchairs -- including manual, powered, custom-made, and the ultra zippy chairs used by athletes. It also makes other medical equipment including crutches, bed systems, respiratory devices, and motorized scooters. It manufactures and sells its own products to home health care and medical equipment dealers in North America, Europe, and the Asia/Pacific region, as well as to government agencies and distributors. Invacare's Supply Group distributes other companies' medical equipment and disposable products, such as home diabetic and wound care items.

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