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Integra LifeSciences Holdings Corporation develops, manufactures, and markets surgical implants and medical instruments for neurosurgery, extremity reconstruction, orthopedics, and general surgery primarily in the United States, Europe, and the Asia Pacific. Its orthopedics product portfolio comprises dermal regeneration and engineered wound dressings to treat the chronic wounds; nerve and tendon for the peripheral nerve repair and protection; bone and joint fixation devices and instruments for upper and lower extremity reconstruction; and bone graft substitutes for extremity reconstruction. The company’s spine and orthobiologics product portfolio includes spinal fusion devices for fusing two vertebrae; supplemental fixation systems for cervical procedures; interbody/vertebral body replacement devices to hold the graft in place to ensure a fusion; orthobiologic products for the repair and regeneration of bone in spinal and trauma surgery; and minimally invasive spine products. Integra’s neurosciences product portfolio includes duraplasty products for managing dural defects; tissue ablation equipment for the ablation of unwanted tissue; cerebral spinal fluid management devices for managing the intracranial pressure of a neuro-compromised patient; cranial stabilization equipment for fixing the head in an orientation determined by the surgeon; and intracranial monitoring equipment for monitoring intracranial pressure and metabolic activity. Its medical instruments product portfolio comprises room instrumentation and surgical lighting; and hand-held surgical instruments for the surgical, dental, podiatry, and animal health markets. Integra LifeSciences Holdings Corporation sells its products directly through various sales forces and other distribution channels. Integra was founded in 1989 and is headquartered in Plainsboro, New Jersey.

ISG was founded in 1975 as Suburban Ostomy; today it is a subsidiary of Invacare. Invacare Supply Group (ISG) makes sure that Invacare's distribution wheels are always greased. ISG, a subsidiary of medical equipment maker Invacare Corporation, is a national wholesale distributor of thousands of medical equipment and supply items, including Invacare-brand wheelchairs and products for orthopedics, diabetes, wound care, ostomy, and urological ailments. Through six regional distribution centers in the US, ISG serves customers including managed care companies, pharmacies, home medical equipment providers, and national home-care chain operators.

IVAX Diagnostics, Inc. is headquartered in Miami, Florida and develops, manufactures and markets proprietary diagnostic reagents, instrumentation and software worldwide through its three subsidiaries; Diamedix Corporation, Delta Biologicals S.r.l. and ImmunoVision, Inc. IVAX Diagnostics, Inc. was created as a result of the merger on March 14, 2001 between b2bstores.com, Inc. and the diagnostic business subsidiary within IVAX Corporation. On January 26, 2006 , IVAX Corporation was merged into a wholly owned subsidiary of Teva Pharmaceutical Industries Ltd. (Teva). As a result of this merger, Teva, indirectly through its IVAX Corporation subsidiary, owned approximately 72% of IVAX Diagnostics. On September 2, 2008 , a group controlled by two experienced and well-known international medical diagnostics and pharmaceutical industry entrepreneurs, Paul Kennedy and Patrice Debregeas, purchased all of the shares of IVAX Diagnostics' common stock owned by Teva and, accordingly, collectively owns approximately 72% of IVAX Diagnostics. IVAX Diagnostics' common stock trades under the ticker symbol IVD on the American Stock Exchange.

Kensey Nash Corporation operates as a medical device company primarily focused on regenerative medicine utilizing its proprietary collagen and synthetic polymer technology. The company specializes in the product development and for applying unique technology in the field of resorbable biomaterials. It offers a range of products, which are sold through strategic partners in multiple medical markets, including, the cardiology, orthopaedic, sports medicine, spine, endovascular, and general surgery markets. Kensey Nash Corporation was incorporated in 1984 and is headquartered in Exton, Pennsylvania.

LeMaitre Vascular, Inc. develops, manufactures, and markets medical devices and implants for the treatment of peripheral vascular disease worldwide. The company’s endovascular products include LeverEdge contrast injector for injection of contrast media into blood vessels; TAArget thoracic stent graft for use in the endovascular repair of thoracic aortic aneurysm and dissection; the UnBalloon non-occlusive modeling catheter for improvement in the seal of aortic stent grafts; and VascuTape radiopaque tape for improvement in precision of vascular and endovascular procedures. Its vascular products consist of AlboGraft vascular grafts for in bypass and replacement procedures; AlboSure and XenoSure vascular patches for use in closing incisions in a blood vessel; AnastoClip vessel closure system for attaching blood vessels primarily for dialysis access; EndoRE remote endarterectomy devices for removal of blockages in the arteries of the leg; expandable LeMaitre valvulotome for destruction of vein valves to create vein bypass grafts; InvisiGrip vein stripper for single-incision removal of varicose veins; LeMaitre balloon catheters for removal of blood clots, occlusion, and facilitation of blood flow; and Pruitt-Inahara, Pruitt F3, and Flexcel carotid shunts for facilitating blood flow to brain during carotid plaque removal. LeMaitre Vascular company’s products in general surgery category comprise reddick cholangiogram catheter for introduction of dye into the cystic duct; and OptiLock implantable port for central venous infusion of drugs and nutrients. In addition, LeMaitre distributes Powerlink system, a bifurcated abdominal stent graft, as well as engages in private label manufacturing. It sells its products through direct sales force and a network of distributors. LeMaitre Vascular was formerly known as Vascutech, Inc. and changed its name to LeMaitre Vascular, Inc. in April 2001. LeMaitre Vascular, Inc. was founded in 1983 and is headquartered in Burlington, Massachusetts.

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