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HMSA was founded in 1989 to increase the profile of Hitachi's medical imaging products in the US. Hitachi Medical Systems America (HMSA) supplies medical imaging equipment to the US hospital market, just as parent Hitachi Medical Corporation (HMC) supplies a full line in Japan. HMSA markets, distributes, and supports HMC's advanced diagnostic imaging products, including computed tomography (CT), magnetic resonance imaging (MRI), and HI VISION brand ultrasound systems. Hitachi Medical Systems America, Inc. is one of the leading distributors of open MRIs in the US. Its parent company's Altaire brand was developed specifically for the US market. Other MRI systems are sold under the Oasis, Echelon, and AIRIS brands.

Hypertension Diagnostics, Inc. engages in the design, development, manufacture, and marketing of devices that non-invasively measure large and small artery elasticity. The company’s products capture blood pressure waveform data produced by the beating heart and analyze it to provide an assessment of systemic arterial elasticity for large and very small arteries. It offers CVProfilor DO-2020 cardiovascular profiling system to primary care physicians and other health care professionals within the United States; HDI/PulseWave CR-2000 research cardiovascular profiling system to clinical research investigators for collecting data in cardiovascular studies; and CVProfilor MD-3000 cardiovascular profiling system. Hypertension Diagnostics, Inc. was founded in 1988 and is based in Eagan, Minnesota.

ICU Medical, Inc. engages in the development, manufacture, and sale of disposable medical connection systems for use in vascular therapy applications in the United States and internationally. Its disposable medical devices protect patients from catheter related bloodstream infections, and healthcare workers from exposure to diseases through accidental needle sticks or hazardous drugs. The company offers I.V. therapy lines consisting of a tube running from a bottle or plastic bag containing an I.V. solution to a catheter inserted in a patient’s vein for use in hospitals and ambulatory clinics; CLAVE product, a needleless I.V. connection device, which could be used with conventional peripheral or central vascular access systems for venous and arterial applications; custom infusion sets, custom oncology sets, and custom critical care sets; and CLC2000, a one piece swabbable connector used to connect I.V. lines to catheters to prevent the back-flow of blood into the catheter. It also provides critical care products that monitor vital signs and specific physiological functions of key organ systems, including pressure monitoring devices, blood sampling systems, angiography kits, sensory catheters, pulmonary artery thermodilution catheters, and multilumen central venous catheters. In addition, the company provides TEGO for use in dialysis; a line of oncology products, including Spiros male luer connector device; the Genie vial access device; the Orbit 90 diabetes set; and custom I.V. sets and ancillary products for oncology therapy. ICU Medical, Inc. sells its products through I.V. product manufacturers and independent distributors, as well as directly to the end users. ICU Medical, Inc. was founded in 1984 and is headquartered in San Clemente, California.

IOP, Inc., headquartered in Costa Mesa, California, is an innovation-driven, medical technology company, providing specialty ophthalmic surgical devices worldwide. IOP, Inc. develops, commercializes and distributes a wide range of technologies to the oculoplastic, glaucoma and cornea subspecialty markets. IOP, Inc., founded in 1988, is focused on leading-edge surgical technologies. IOP, Inc. has leadership positions with bioimplants and devices for ophthalmic plastic and reconstructive surgeries; glaucoma implant drainage technology; and bioimplants for a wide range of ophthalmic surgical applications.Through intimate relationships with key clinical and market leaders, IOP, Inc. has an established and focused technology-development pipeline. Innovative Ophthalmic Products believes it will lead to differentiated, unique technologies that will satisfy unmet surgeon and patient demands. IOP, Inc. uses a variety of innovative methods and strategic collaborations to develop and deliver technologies offering solutions. Innovative Ophthalmic Products has formed and currently maintains strategic alliances with OKTO Ophtho, Tutogen Medical, Inc., Molteno® Ophthalmic Ltd., Advanced Meditech International Inc. and Osmed GbH.

Integra LifeSciences Holdings Corporation develops, manufactures, and markets surgical implants and medical instruments for neurosurgery, extremity reconstruction, orthopedics, and general surgery primarily in the United States, Europe, and the Asia Pacific. Its orthopedics product portfolio comprises dermal regeneration and engineered wound dressings to treat the chronic wounds; nerve and tendon for the peripheral nerve repair and protection; bone and joint fixation devices and instruments for upper and lower extremity reconstruction; and bone graft substitutes for extremity reconstruction. The company’s spine and orthobiologics product portfolio includes spinal fusion devices for fusing two vertebrae; supplemental fixation systems for cervical procedures; interbody/vertebral body replacement devices to hold the graft in place to ensure a fusion; orthobiologic products for the repair and regeneration of bone in spinal and trauma surgery; and minimally invasive spine products. Integra’s neurosciences product portfolio includes duraplasty products for managing dural defects; tissue ablation equipment for the ablation of unwanted tissue; cerebral spinal fluid management devices for managing the intracranial pressure of a neuro-compromised patient; cranial stabilization equipment for fixing the head in an orientation determined by the surgeon; and intracranial monitoring equipment for monitoring intracranial pressure and metabolic activity. Its medical instruments product portfolio comprises room instrumentation and surgical lighting; and hand-held surgical instruments for the surgical, dental, podiatry, and animal health markets. Integra LifeSciences Holdings Corporation sells its products directly through various sales forces and other distribution channels. Integra was founded in 1989 and is headquartered in Plainsboro, New Jersey.

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