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Southern Research Institute performs contract research in areas such as drug development and discovery, engineering, and environmental and energy issues. The not-for-profit organization launched a life science R&D consulting firm, BioSafety Solutions, in 2008. Southern Research Institute's clients have included government agencies such as the National Institutes of Health, the US Department of Defense, and NASA as well as corporate clients Mercedes-Benz and Southern Company. Southern Research Institute tests anti-influenza and anti-HIV drugs for NanoViricides Inc. Founded in 1941, Southern Research Institute has been affiliated with the University of Alabama at Birmingham since 1999.

Southwest Research Institute was founded in 1947 by oilman and rancher Thomas Slick Jr., Southwest Research Institute (SwRI) is an independent, not-for-profit research and development institution that contracts to explore subjects in areas including automation and data systems, applied physics, space science and engineering, and chemistry. SwRI has about 3,000 scientists, engineers, and support staff at its 23 laboratories and offices in the US, China, and the UK. Customers include the private sector and government agencies. SwRI's subsidiary, Signature Science, researches national security, environmental management, and biotechnology.

Spire Corporation engages in the development, manufacture, and marketing of engineered products and services in the areas of PV solar, biomedical, and optoelectronics. Spire Corporation offers specialized equipment for the production of terrestrial photovoltaic modules from solar cells; photovoltaic systems for application to powering buildings with connection to the utility grid; and photovoltaic materials. Spire Corporation also provides surface treatments to manufacturers of orthopedic and other medical devices; and performs sponsored research programs into practical applications of advanced biomedical and biophotonic technologies. In addition, Spire Corporation offers custom compound semiconductor foundry and fabrication services to customers involved in biomedical/biophotonic instruments, telecommunications, and defense applications. Spire Corporation also involves in compound semiconductor wafer growth, thin film and related device processing, and fabrication services. Further, the company provides materials testing services, as well as offers services in support of sponsored research into practical applications of optoelectronic technologies. Spire Corporation sells its products and services primarily through its independent sales representatives and distributors in the United States, Europe, north Africa, Asia, and rest of the world. Spire Corporation was founded in 1969 and is headquartered in Bedford, Massachusetts.

SRI International "Silicon Valley's soul," the not-for-profit think tank ponders advances in biotechnology, chemicals and energy, computer science, electronics, and public policy -- and ways to commercialize those advances. SRI focuses on technology research and development, business strategies, and issues analysis. SRI International has patents and patent applications in such areas as information sciences, software development, communications, robotics, and pharmaceuticals. SRI's clients have included Visa, Samsung, NASA, and the US Department of Defense. Originally founded in 1946 as Stanford Research Institute, SRI became fully independent of Stanford University in 1970.

Standard Rate and Data Service, which does business as SRDS, collects and distributes information on media advertising rates and other data of interest to advertisers and their media planning agencies. In addition to ad rates, Standard Rate and Data Service, Inc. collects publishing dates and contact data on more than 100,000 media outlets in the US. SRDS offers information products tailored to customers in advertising, direct marketing, and public relations. In 2008 Nielsen traded SRDS to WPP in exchange for other assets. SRDS is part os WPP's global market research organization The Kantar Group.

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