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ROHTO Pharmaceutical Co., Ltd. company was founded by Yasutami Yamada in 1899 as Shintendo Yamada Anmin Pharmacy. Later, it changed its name to Rohto Pharmaceutical Co., Ltd. in 1949. Rohto Pharmaceutical is headquartered in Osaka, Japan. Rohto Pharmaceutical Co., Ltd. engages in the manufacture and marketing of pharmaceutical and other healthcare products in Japan and internationally. It primarily offers eye care, skin care, and oral medicine and supplement products. The company's eye care products include eye drops, eye wash preparations, and contact lens care products. Its eye care products spreads moisture over the surface of the eyes, suppresses allergy and works on ocular itching, as well as are used for the treatment of sties and conjunctivitis, inflammation or itching caused by bacteria on lenses, and eye disease causing pollens and house dust.Rohto company's skin care products include dermal medicines, which are used for the treatment of dry skin and females' anorectal discomforts; lip care products that are used for the prevention of dry, sore, and roughness of lips; and hand, body, sun, and acne care products. Rohto Pharmaceutical's oral medicine and supplement products include `Pansion' brand products, which are primarily used for the treatment of gastric discomfort, mucosal repair agents and stomachics for improving damaged gastric mucosa, stomach pain, and heartburn and other hyperacidity-related symptoms. It also offers a range of test products, including blood sugar testing kits, ovulation self-test kits, and pregnancy self-test kits; and denture cleansers.

Sanjiu Enterprise Group is really into pushing drugs. Of course, being state-owned, these are drugs of the legal variety. Sanjiu Enterprise Group company operates Shenzhen 999 Chinese Medicine Investment & Development Company, which manufactures over-the-counter drugs designed to treat minor illnesses; it also produces prescription drugs like traditional Chinese injections, biomedicines, and antibiotics. Sanjiu also operates 20 other pharmaceutical subsidiaries with more than 1,000 types of herbal and other medicines in production. It markets its products under the "999" (a.k.a. "three nines", representing luck and balance in Chinese) brand; it also supplies equipment and printing services to the medical community.

Sanofi Pasteur MSD Limited company makes a range of vaccines for adults and children in the UK, as well as vaccines for those traveling abroad; it is the largest producer of vaccines in the UK. It makes about 20 vaccines including those for influenza, polio, hepatitis A and B, rabies (discovered by namesake Louis Pasteur), yellow fever, and tetanus. Sanofi Pasterur company has also developed Gardasil, a vaccine against types of human papillomavirus (HPV) known to cause cervical cancer. Sanofi Pasteur MSD is a joint venture between the vaccine division of Sanofi-Aventis and drug firm Merck, which each own half of the company.

Sanofi-Aventis was founded in 1970 and is headquartered in Paris, France. Sanofi-Aventis is a pharmaceutical group engaged in the research, development, manufacture and marketing of healthcare products. The Company's business includes two main activities: pharmaceuticals and human vaccines through sanofi pasteur. In its pharmaceutical activity, Sanofi-Aventis specializes in six therapeutic areas: thrombosis, cardiovascular, metabolic disorders, oncology, central nervous system (CNS) and internal medicine. The Company offers vaccines in five areas: pediatric combination vaccines, influenza vaccines, adult and adolescent booster vaccines, meningitis vaccines, and travel and endemic vaccines. On September 1, 2008, Sanofi-Aventis acquired the Australian company, Symbion CP Holdings Pty Ltd (Symbion Consumer). On September 25, 2008, it acquired Acambis plc. In January 2009, the Company sold its French plant of Colomiers to French pharmaceutical company Unither. In April 2009, the Company acquired Mexican generic company, Laboratorios Kendrick.

Sanofi-Aventis Deutschland boasts itself as one of the largest pharmaceutical businesses in the country. A subsidiary of French giant Sanofi-Aventis, the company manufactures and markets prescription and over-the-counter drugs. Along with its Lantus and Insuman insulin products, Sanofi-Aventis Deutschland produces Plavix and Lovenox. The company also dedicates much of its efforts on research and development at its Frankfurt, Germany headquarters and is focused on metabolic illnesses such as diabetes, as well as cancer and cardiovascular diseases.

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