
ArQule, Inc. was founded in 1993 and is headquartered in Woburn, Massachusetts. ArQule, Inc. is a clinical-stage biotechnology company engaged in the research and development of cancer therapeutics. The Company’s product is ARQ 197, an orally administered inhibitor of the c-Met receptor tyrosine kinase. ARQ 197 is being evaluated as monotherapy and in combination therapy in a Phase II clinical development program that includes trials in Microphthalmia Transcription Factor (MiT) associated tumors, non-small cell lung cancer (NSCLC), pancreatic adenocarcinoma and hepatocellular carcinoma (HCC). The Company has licensed commercial rights to ARQ 197 for human cancer indications to Daiichi Sankyo Co., Ltd. (Daiichi Sankyo) in the United States, Europe, South America and the rest of the world, excluding Japan and certain other Asian countries, where it has licensed commercial rights to Kyowa Hakko Kirin Co., Ltd. (Kyowa Hakko Kirin).

IGI Laboratories, Inc. was founded in 1977 and is headquartered in Buena, New Jersey. IGI Laboratories, Inc. engages in the development, manufacture, filling, and packaging of topical, semi solid, and liquid products for pharmaceutical, cosmeceutical, and cosmetic companies. The company focuses on the commercialization of its licensed Novasome encapsulation technology for skin care/treatment products. It licenses the Novasome encapsulation technology from Novavax, Inc. for applications in animal pharmaceuticals, biologicals, and other animal health products; foods, food applications, nutrients, and flavorings; cosmetics, consumer products, and dermatological over-the-counter and prescription products; fragrances; and chemicals, including herbicides, insecticides, pesticides, paints and coatings, photographic chemicals, and other specialty chemicals, as well as the processes for making the same. The company was formerly known as IGI, Inc. and changed its name to IGI Laboratories, Inc. in May 2008.

Perrigo Company was founded in 1887 and is headquartered in Allegan, Michigan. Perrigo Company is a global healthcare supplier that develops, manufactures and distributes over-the-counter and prescription pharmaceuticals, nutritional products, active pharmaceutical ingredients, and pharmaceutical and medical diagnostic products. The Company operates in three segments: Consumer Healthcare, Rx Pharmaceuticals and API. The Company has other category that consists of the Israel Pharmaceutical and Diagnostic Products. The Company operates through wholly owned subsidiaries. In the United States, its operations are conducted through L. Perrigo Company, Perrigo Company of South Carolina, Inc., Perrigo New York, Inc., Perrigo Holland, Inc. and Perrigo Florida, Inc. Outside the United States, its operations are conducted through Perrigo Israel Pharmaceuticals Ltd., Chemagis Ltd., Quimica y Farmacia S.A. de C.V., Laboratorios Diba, S.A., Wrafton Laboratories Limited, Brunel Pharma Limited and Galpharm Healthcare Ltd.

Founded in the early 1900s, LEO Pharma has about two dozen products on the market, many of which treat psoriasis, eczema, and skin infections. The company's other focus areas include developing and manufacturing treatments for blood clot disorders, kidney disease, and support drugs for cancer treatments. Products such as Daivobet, Innohep, and Xamiol are among its best sellers. LEO Pharma has operations in Europe, as well as in the US, Middle East, Africa, and Asia. The company is wholly-owned by the Leo Foundation, which is managed by members of LEO Pharma's executive team.

EXACT Sciences Corporation company was founded in 1995 and is based in Madison, Wisconsin. Exact Sciences Corporation, a molecular diagnostics company, focuses on the early detection and prevention of colorectal cancer. The company has exclusive intellectual property protecting its non-invasive, molecular screening technology for the detection of colorectal cancer. Its non-invasive stool-based DNA (sDNA) screening technology includes proprietary and patented methods that isolate and analyze human DNA present in stool to screen for the presence of colorectal pre-cancer and cancer. The company's principal product includes ColoSure, a non-invasive laboratory developed stool-based DNA testing service for the detection of colorectal cancer in the average-risk population. Exact Sciences Corporation has strategic alliances with Laboratory Corporation of America Holdings, the MAYO Foundation for Medical Education and Research, and Genzyme Corporation.

RBC Life Sciences, Inc. was founded in 1988 and is headquartered in Irving, Texas. RBC Life Sciences, Inc., together with its subsidiaries, markets and distributes nutritional supplements and personal care products primarily in the United States, the former Soviet Union, and Canada. It operates in two segments, Nutritional Products and Medical Products. The Nutritional Products segment provides a line of approximately 75 nutritional supplements and personal care products, including herbs, vitamins, and minerals, as well as natural skin, hair, and body care products under the RBC Life Sciences brand. It markets these products in various categories comprising wellness products, weight loss products, fitness products, and skin care products. This segment markets its products through a network of independent associates, as well as through licensing arrangements with third parties. The Medical Products segment markets a line of approximately 28 wound care products under the MPM Medical brand name.RBC Life Sciences's products include cleansers, dressings, hydrogels, calcium alginates, moisture barriers, antimicrobials, and a hydrogel wound dressing with Lidocaine, as well as other products, which reduce destruction to skin and tissue caused by radiation, and to reduce pain and itching caused by radiation reactions in the skin and the internal mucosa caused by radiation reactions or reactions to certain cancer medications. Its wound care products are used for the treatment and healing of wounds, such as pressure ulcers, leg ulcers, cuts, burns, and abrasions, as well as to manage pain associated with these wounds in the acute care, long-term care, oncology, and podiatry markets. This segment distributes products to hospitals, nursing homes, clinics, pharmacies, and home health care agencies through medical/surgical supply dealers and pharmaceutical distributors.

PML Microbiologicals, Inc. company was founded in 1969 and is headquartered in Wilsonville, Oregon. It has manufacturing facilities in Mississauga, Canada; and Portland, Oregon. As of December 8, 2008, PML Microbiologicals, Inc. operates as a subsidiary of BioMérieux S.A. PML Microbiologicals, Inc. manufactures culture media and microbiological products for clinical and industrial applications in North America. It offers prepared culture media, stains, reagents, quality control organisms, sterility products, and collection and transport systems, as well as accessories for microbiology laboratories. The company also provides custom products, such as minimum inhibitory concentration panels, parasitology kits, diluents, and rinsing fluids. It serves clinical, pharmaceutical, research, environmental, personal care, and food and beverage industries. PML Microbiologicals, Inc. was formerly known as Prepared Media Laboratory.

Dow Pharmaceutical Sciences company researches and develops topical dermatological pharmaceutical and biotech products for external clients. It works to formulate the gel, ointment, or cream that will carry a client's drug, assesses its effectiveness, manufactures and packages product candidates for clinical trials, and provides regulatory affairs consulting. It provides contract research services through its Solano Clinical Research division in the US and its Bioskin subsidiary in Europe. Dow Pharmaceutical Sciences also develops dermatology products on a proprietary basis. The company is owned by Valeant Pharmaceuticals.

Roxane Laboratories, a US-based subsidiary of Germany's Boehringer Ingelheim, oversees the development, manufacturing, and marketing of its parent company's multisource (generic) drugmaking business in the US. It sells about 75 medications in 250 package sizes, focusing on oral liquids, sustained-release and controlled-release tablets, cancer drugs, and nasal sprays. It also distributes narcotics, such as meperidine (generic Demerol) and methadone. Products developed and marketed by Roxane are manufactured by its sister company, Boehringer Inghelheim Roxane, also located in Columbus, Ohio.

China National Pharmaceutical Group (SINOPHARM) is the largest pharmaceutical company in the world's most populous nation. The company researches and develops, manufactures, distributes, and markets medicine and other healthcare products. SINOPHARM manages factories, research laboratories, traditional Chinese medicine plantations, and marketing and distribution networks that extend throughout the country. It also has 10 subsidiaries and a number of major joint ventures. The company also runs about a dozen retail pharmacy chains. SINOPHARM, which has operations in Africa, France, Germany, Hong Kong, the US, and Vietnam, was formed in 1998. The Chinese government controls the pharmaceutical firm.
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