Lyne Laboratories contract pharmaceutical manufacturer specializes in oral liquid formulations (with a bitter-taste blocker available), as well as powder-form, semi-solid, and tablet medicines. The company also offers analytical services, such as quality control and testing, and regulatory support services. Lyne Laboratories can whip up small test-size batches for clinical research as well as full production for commercial launches and provide regulatory support along the way. An explosion-proof production and storage facility has expanded its ability to produce flammable drugs.

Sovereign Pharmaceuticals was founded in 1990. Sovereign Pharmaceuticals, Ltd. company arms its customers with made-to-order OTC and prescription medications that combat gastrointestinal, respiratory, and cold symptoms. Its manufacuring plant has the capacity to make more than 3 million pints of liquid and more than 650 million tablets a year. Other capabilities include the manufacture of creams, ointments, and suspensions. In addition, the company offers custom packaging and research and development services.

Cephalon, Inc. was founded in 1987 and is headquartered in Frazer, Pennsylvania. Cephalon, Inc., a biopharmaceutical company, engages in the discovery, development, and commercialization of products for central nervous system, inflammatory disease, pain, and oncology therapeutic areas. Its products for central nervous system disorders include PROVIGIL for the treatment of excessive sleepiness associated with narcolepsy, obstructive sleep apnea/hypopnea syndrome, and shift work sleep disorder; NUVIGIL, a single-isomer formulation of modafinil; and GABITRIL for use as an adjunctive therapy in the treatment of partial seizures in epileptic patients. The company's pain therapeutics portfolio comprises AMRIX for the relief of muscle spasm associated with acute painful musculoskeletal conditions; and FENTORA, EFFENTORA, ACTIQ, and generic OTFC products, which focus on treating breakthrough cancer pain in opioid-tolerant patients. Its products for oncology consist of TREANDA, a bi-functional hybrid cytotoxic; TRISENOX, an intravenous arsenic-based targeted therapy; CEP-701, an oral small molecule tyrosine kinase inhibitor; MYOCET, a cardio-protective chemotherapy agent to treat metastatic breast cancer; TARGRETIN for the treatment of cutaneous T-cell lymphoma; and ABELCET, an anti-fungal product for cancer patients. The company provides its products principally to wholesale drug distributors. It has collaboration agreements with Euroscreen s.a.; Ligand Pharmaceuticals Incorporated; Psychogenics Inc.; and AMBIT Biosciences Inc, as well as a research agreement with Celator Pharmaceuticals Inc. Cephalon, Inc. markets its products primarily in the United States, Europe, the Middle East, and Africa.

Celgene Signal Research (also known as Celgene Research San Diego) wouldn't want it any other way. This Celgene division works to identify potential drug candidates with a focus on regulating genes and the production of disease-causing proteins. Much of its work has been to identify and map certain kinase and ligase proteins, which future Celgene drugs are then designed to inhibit. Celgene Signal Research's drug discovery programs target inflammatory diseases, as well as cancers such as leukemia.

Newron Pharmaceuticals focuses its brainpower on finding remedies for nervous system disorders. As a biopharmaceutical company focused on developing treatments for central nervous system diseases, Newron is developing a pipeline that includes treatments for Parkinson's disease and neuropathic back pain (pain which results from damage to nerve cells). The company is also in the early stages of developing treatments for Restless Leg Syndrome and Alzheimer's disease, as well as other neuropathic pain disorders. Newron is currently partnered with Merck Serono for development of Newron's primary drug product Safinamide, a Parkinson's treatment.

Pain Therapeutics, Inc. was founded in 1998 and is based in San Mateo, California. Pain Therapeutics, Inc., a biopharmaceutical company, engages in the research and development of novel drugs. It has four drug candidates in clinical development programs, which include Remoxy, a novel controlled-release oral capsule form of oxycodone; PTI-202 and PTI-721, which are abuse-resistant forms of opioid drugs; and PTI-188 for the treatment of metastatic melanoma. The company is also developing a technology for the treatment of hemophilia in patients. Pain Therapeutics, Inc. has a strategic alliance with King Pharmaceuticals, Inc. for the development and commercialization of Remoxy, PTI-202, PTI-721, and other abuse-resistant opioid painkillers.

Amerifit Brands aims to calm the irritating tickles, hot flashes, and pains that accompany everyday life. The company develops, markets, and distributes a variety of natural, non-prescription products blended from herbs, minerals, pharmaceuticals, and vitamins. Amerifit's brands include AZO and Estroven (women's wellness), Flex Able (joint health), Sootherbs (cough and cold remedies), and Vitaball (children's multivitamin). Its products take a variety of forms, including lozenges, gumballs, gels, and pills. The company's products are primarily sold in chain drug stores and mass market retailers. Amerifit is owned by private equity firm Charterhouse Group and has agreed to be acquired by Martek Biosciences.

Brothers Charles and Theophil Gebauer founded the company in 1898. Gebauer's Salivart will make your mouth water. Seriously, that's what it's designed to do for people who suffer from xerostomia, better known as dry mouth. That's not all Gebauer makes, however. The company offers medications for topical use, including Ethyl Chloride for the treatment of pain; Instant Ice, for the relief of muscle spasms, strains, bruising, and other injuries; and Spray and Stretch, for myofacial pain and minor sports injuries. Gebauer also provides contract manufacturing as well as project planning, packaging and labeling, and distribution services for other drug makers.

LipoScience, Inc. company was founded in 1994 by its chief scientific officer, Dr. James Otvos. LipoScience, Inc. company's primary product, the NMR LipoProfile, uses nuclear magnetic resonance (NMR) therapy to analyze blood samples and assess the levels of lipoprotein particles in the bloodstream. (Such particles contain cholesterol, and detection of them can help pinpoint cardiovascular risks.) The LipoProfile differs from other cholesterol tests in that it does not require physical separation of the particles. LipoScience markets the LipoProfile and other traditional diagnostic tests through a direct sales force to health care providers and research labs.

Boiron believes in nature's cures. The company makes homeopathic remedies to combat such maladies as colds, the flu, allergies, and anxiety. Founded in 1911, it is one of the oldest and largest such firms in Europe. It dominates its home market of France and also operates in Africa, Australia, North and South America, and the Middle East through about 20 subsidiaries. Along with homeopathic remedies, Boiron develops personal, animal care, and nutritional products for sale in some markets, including France (but not the US). One of the company's key products is Oscillococcinum six-dose homeopathic flu medicine. Used throughout the world, Oscillo is one of the largest homeopathic flu medicines in the US.

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