Vermillion, Inc. is involved in the discovery, development and commercialization of diagnostic tests that help physicians diagnose, treat and improve outcomes for patients. The Company uses the process of utilizing advanced protein separation methods to identify and resolve variants of specific biomarkers (known as translational proteomics) for developing a procedure to measure a property or concentration of an analyte (known as an assay) and commercializing diagnostic tests. Vermillion has focuses in the areas of oncology, hematology, cardiology and women’s health. Vermillion’s focus on translational proteomics enables it to address the market for diagnostic tests that measure multiple protein biomarkers. In January 2010, the Company emerged from protection under Chapter 11 of the United States Bankruptcy Code.

Boehringer Ingelheim Chemicals (BIC) is active in active ingredients. BIC is the chemical manufacturing arm of Boehringer Ingelheim Corporation, the US division of German pharmaceutical company Boehringer Ingelheim. BIC is a leading maker of active pharmaceutical ingredients and drug intermediates. The company operates a DEA-approved facility where it makes a range of chemicals from controlled substances such as methadone to cough medicine ingredient guaifenesin. BIC supplies other divisions of Boehringer Ingelheim, as well as third parties in the pharmaceutical and food industries.

Acurian hopes you can help them find a cure for everything from cancer to anxiety disorders. Acurian company matches up biotech, pharmaceutical, and medical device companies with patients interested in participating in clinical trials for experimental and innovative therapies. The company's website allows interested patients to register their ailments and express their willingness to participate. All this has helped Acurian develop a database of over 50 million interested people, which it connects with about 60 pharma and biotech companies. The company also develops software to help contract research organizations (CROs) manage and track the results of clinical trials.

Otsuka Pharmaceutical Co. (OPC) is a manufacturer and distributor of pharmaceuticals, clinical testing and medical equipment, and food products. The company operates six business segments specializing in branded prescriptions, over-the-counter drugs, clinical nutritionals, diagnostic substances and devices, nutraceuticals, and skin care products ("cosmedics"). OPC's medicinal products include Mikelan eye drops for glaucoma treatment and Pletaal anti-platelet treatment. The company's line of nutraceutical consumer health products include FIBE-MINI dietary fiber supplement, Calorie Mate foods, and Pocari Sweat sports drink. Otsuka Pharmaceutical is part of the very diverse Otsuka Group.

UCB SA is a Belgium-based biopharmaceutical and specialty chemical company that specializes in two therapeutic areas: diseases of the central nervous system (CNS) and immunology. In the area of central nervous system disorders, the Company is focused on epilepsy, diabetic neuropathic pain, multiple sclerosis, fibromyalgia, restless legs syndrome and Parkinson’s disease, and in the area of immunology on allergies, bone loss disorders, Crohn’s disease, rheumatoid arthritis and Systemic lupus erythematosus. UCB SA delivers small and large molecule solutions to specialists for use in the treatment of severe diseases. UCB also has a selective presence in primary care. The Company, together with its subsidiaries, has research and development facilities in Belgium, Germany, Japan, the United Kingdom and the United States. As of December 31, 2008, UCB SA had a number of wholly owned subsidiaries in the United States, Canada, Europe, Asia, South America and Australia.

GeneThera, formerly called Hand Brand Distribution, develops genetic diagnostic assays for the agriculture and veterinary industries. The biotech company has developed assays that detect Chronic Wasting Disease in elk and deer, and Mad Cow Disease in cattle. The company is working on cancer detection tests for animals, as well as similar tests for humans, through its partnership with Xpention, a biotechnology company focused on oncology diagnostics. GeneThera is also developing vaccines for animal diseases, such as E. coli.

Paratek Pharmaceuticals Inc. company is working to create new forms of tetracycline that will be effective against newly resistant strains of bacteria and potentially treat diseases not associated with bacteria, including neurodegenerative and inflammatory conditions such as rheumatoid arthritis. It has synthesized more than 2,500 new tetracycline compounds and is sifting through each to find their possible applications. The company's Multiple Antibiotic Resistance Program (MAR) is looking at ways to genetically turn off bacteria's ability to survive, thereby preventing infection in the first place.

Altea Therapeutics Corporation company was founded in 1998 and is based in Atlanta, Georgia. Altea Therapeutics Corporation, a pharmaceutical company, develops and commercializes transdermal patch technology that delivers therapeutic levels of water-soluble small drugs, therapeutic proteins, carbohydrates, and vaccines through the skin. It provides disease prevention products, insulin skin patches for diabetes, and acute and chronic pain management products. The company also offers PassPort Patch to deliver drugs through the skin. Altea Therapeutics Corporation was formerly known as Altea Development Corporation.

EMD Serono develops a potpourri of prescription pharmaceuticals used for the treatment of neurological, metabolic, and fertility disorders and diseases such as multiple sclerosis (MS), lupus, and HIV. The Massachusetts-based company conducts research and development programs in the US and markets products that include Gonal-f, Luveris, Ovidrel, Rebif, and Zorbtive in the US and Canada. The company has manufacturing and marketing agreements with other pharmaceutical firms, including Pfizer (MS) and CuraScript (fertility). EMD Serono is the North American operating subsidiary of Merck Serono S.A..

Medicure Inc., (Medicure) is a biopharmaceutical company engaged in the research and development and commercialization of human therapeutic. The Company's primary focus is on the sale and marketing of its acute care cardiovascular drug, AGGRASTAT (tirofiban hydrochloride) in the United States and its territories through its United States subsidiary, Medicure Pharma Inc. The Company's primary research and development program of focus is the clinical development of TARDOXAL (product previously referred to as AVASTREM) for neurological disorders, although the Company continues to investigate and advance certain other product opportunities.

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