Oxford BioMedica has no reservations about launching attacks on disease. The biotechnology company focuses on developing gene therapy treatments for oncology and neurotherapy. Its lead product,TroVax, is in testing for renal and colorectal cancer and is designed to stimulate the body's immune response to attack tumor cells. Another leading candidate, ProSavin, is in testing for treatment of Parkinson's disease. The company has several additional products in various stages of clinical development. Oxford BioMedica has awarded Sanofi-Aventis exclusive rights to develop and commercialize TroVax globally. The company's California-based BioMedica subsidiary handles its business development in North America and Asia.

Rib-X Pharmaceuticals, Inc. designs and develops novel small-molecule antibiotics for the treatment of serious infections. Its products include delafloxacin, which is used for complicated skin and soft tissue infections; and radezolid, which is used for community acquired pneumonia, and uncomplicated skin and soft tissue infections. The company’ products are also used for the treatment of serious hospital gram-negative infections. Rib-X Pharmaceuticals, Inc. was founded in 2000 and is based in New Haven, Connecticut.

Vaccination is one of the most effective methods of preventing infectious diseases. That’s why Janssen Vaccines is committed to developing first-in-class or best-in-class vaccines for some of the world’s most life- threatening infectious diseases such as Ebola, Respiratory Syncytial Virus (RSV), Human Immunodeficiency Virus (HIV), Extra-intestinal Pathogenic E. coli (ExPEC) and polio. Most of our pipeline products are based on two innovative technology platforms – PER.C6® and AdVac®. We partner with many of the world’s leading experts, academic and clinical institutions and other pharmaceutical companies for the development of vaccines.

BioNumerik Pharmaceuticals does biopharmaceutical drug development by the numbers. Using a multi-discipline process of identifying potential cancer drugs, the company has brought two candidates into late-stage development. Lead candidate Tavocept, which has FDA fast-track status, may prevent nerve and kidney damage caused by cancer therapies. BioNumerik's Karenitecin candidate is an advanced formulation of an existing cancer drug and is being evaluated for treatment of solid tumors. The firm relies heavily on computer models and simulations to identify promising drug candidates. In addition to its two lead candidates, it has several other potential drugs in pre-clinical research.

AVANIR Pharmaceuticals, Inc. was founded in 1988 and is headquartered in Aliso Viejo, California. AVANIR Pharmaceuticals, Inc. focuses on acquiring, developing, and commercializing novel therapeutic products for the treatment of central nervous system disorders primarily in the United States and Canada. Its lead product candidate includes Zenviatm, which has completed three Phase III clinical trials for the treatment of pseudobulbar affect; and a Phase III trial for the treatment of patients with diabetic peripheral neuropathic pain. The company also offers Abreva, an over-the-counter product for the treatment of cold sores.

Pfizer decided to put a Cork in it, the pharmaceutical giant made Ireland one of the world's largest manufacturers and exporters of pharmaceuticals. Pfizer Ireland Pharmaceuticals is part of the Pfizer Global Manufacturing division. Parent company Pfizer began operating in Ireland in 1969 with a citric acid manufacturing plant and now operates about a dozen Irish plants. Its manufacturing facilities are involved in the development, formulation, and bulk manufacture of human pharmaceuticals (especially cardiovascular drugs) and animal health care products, as well as sterile pharmaceutical products and active pharmaceutical ingredients.

Reliv' International, Inc. was founded in 1984 and is headquartered in Chesterfield, Missouri. Reliv' International, Inc. is a developer, manufacturer and marketer of a line of nutritional supplements addressing basic nutrition, specific wellness needs, weight management and sports nutrition. The Company offers 16 nutritional supplements and a line of seven skin care products. Its core line of nutritional supplements, which represented 64.5% of net sales, during the year ended December 31, 2008, includes four products: Reliv Classic and Reliv NOW, two basic nutritional supplements containing a full and balanced blend of vitamins, minerals, proteins and herbs; Innergize!, an isotonic sports supplement in three flavors, and FibRestore, a high-fiber and antioxidant supplement. The Company’s product line includes nutritional supplements that address basic nutrition, specific wellness needs, weight management and sports nutrition.

Spectrum Laboratories is wrapped up in a full gamut of filtration products. Spectrum operates three product groups: bioprocessing (membranes, membrane devices, diagnostics, and pharmaceuticals), Original Equipment Manufacturing (or "OEM", which supplies filtration and separation devices to companies making in vivo and ex-vivo filtration devices), and disposable operating room products (orthopedic and arthroscopic drapes, sterile microscope covers, tissue carriers, and other disposables). Spectrum also does contract manufacturing to create customized products with filtration applications for laboratory use. It has three production facilities in the US along with sales offices in the Netherlands and Japan.

New Brunswick Scientific Co. was founded in 1946 and is headquartered in Edison, New Jersey. As of September 24, 2007, New Brunswick Scientific Co. Inc. is a subsidiary of Eppendorf AG. New Brunswick Scientific Co., Inc. and its subsidiaries provide various research equipment and scientific instruments for the life sciences industry. It engages in the design, manufacture, and marketing of equipment that creates, maintains, measures, and controls the physical and biochemical conditions required for the growth, detection, and storage of biological cultures. The company’s products include fermentation equipment, bioreactors, biological shakers, ultra-low temperature freezers, CO2 incubators, nutrient sterilizing and dispensing equipment, tissue culture apparatus, and air samplers. Its products are used in medical, biological, chemical, and environmental research; and for the commercial development of antibiotics, proteins, hormones, enzymes, monoclonal antibodies, agricultural products, fuels, vitamins, vaccines, and other substances. The company sells its equipment to biotechnology and pharmaceutical companies; agricultural and chemical companies; other industrial customers engaged in biotechnology; and medical schools, universities, research institutes, hospitals, and private laboratories; and laboratories of federal, state, and municipal government departments and agencies. It also sells its equipment directly, as well as through scientific equipment dealers to foreign companies, institutions, and governments. The company primarily operates in the United States, Asia, and Europe.

Senetek PLC (Senetek) is a life sciences company engaged in the development of technologies that target the science of healthy aging. The Company’s business consists of two business segments: dermatological/skincare compounds principally addressing photoaging and other skincare needs (Skincare), and pharmaceuticals, principally those addressing sales of monoclonal antibodies, sexual dysfunction and drug delivery of liquid injectable products (automatic injectors) (Pharmaceutical). The Skincare segment’s products include Pyratine-6, 4HBAP and Kinetin. The Pharmaceutical segment’s products include Invicorp, Reliaject, and diagnostic monoclonal antibodies used in Alzheimer’s and other disease research, which the Company licenses from Research Foundation for Mental Hygiene (RFMH) and sells to Covance Antibody Services Inc. The Company has three wholly owned subsidiaries, Senetek Drug Delivery Technologies Inc. (SSDT), Carme Cosmeceutical Sciences Inc. (CCSI) and Senetek Denmark ApS.

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