CEL-SCI Corporation was founded in 1983 and is based in Vienna, Virginia. CEL-SCI Corporation, is engaged in the development of a product called Multikine for the treatment of cancer. It simulates the activities of a healthy person's immune system, which battles cancer every day. Multikine is multi-targeted, it is the cancer immunotherapy that both kills cancer cells in a targeted fashion and activates the general immune system to destroy the cancer. Multikine is a type of immunotherapy in that it is immunotherapy, incorporating both active and passive immune activity.

Forbes Medi-Tech has an answer for folks wanting to lower their cholesterol by changing their diet. The firm makes Reducol, a dietary supplement ingredient that reduces LDL, the "bad" cholesterol associated with increased risk of heart disease. It sells the ingredient to food and nutritionals companies that incorporate it into their products. Pharmavite uses Reducol in its Cholest-Off supplement, and foodmakers in Europe use it in items such as yogurt, milk, and bread. Until 2008 Forbes Medi-Tech also had a drug development operation, which was testing pharmaceutical candidates to treat high cholesterol and metabolic conditions; however, it has divested those operations to focus on its Reducol business.

NanoBio is trying to put its NanoStat antimicrobial nanoemulsion technology to work enabling drugs that treat topical and mucosal diseases. The firm's nanoemulsions are formulated to destroy such bacteria as "E. coli", as well as fungi, spores, and viral invaders. NanoBio's two lead candidates are in development to treat cold sores and nail fungus. Other candidates target acne, genital herpes, herpes zoster (better known as shingles), drug-resistant bacterial infections, and viral respiratory infections. NanoBio is also exploring how to use its technology to develop vaccines for hepatitis B and influenza.

Acorda Therapeutics, Inc. (Acorda) is a commercial-stage biopharmaceutical company engaged in the identification, development and commercialization of therapies that improve neurological function in people with multiple sclerosis (MS), spinal cord injury (SCI), and other disorders of the central nervous system (CNS). The Company’s marketed product, Zanaflex Capsules, is approved by the United States Food and Drug Administration (FDA) for the management of spasticity. The Company’s product candidate Fampridine-SR, has completed two positive Phase III clinical trials for the improvement of walking ability in patients with MS. The research and development programs for the Company include Remyelination Programs and Chondroitinase Program.

Penn Pharmaceutical Services wants to help you by helping others, specifically pharmaceutical companies. Penn offers a variety of products and services: clinical trial supplies; formulation and analytical development; chemistry, manufacturing, and controls (CMC) consultancy; qualified person (QP) audits; and contract manufacturing services. It also offers logistical management services, such as exporting and reporting. In 2007 Penn, which serves many US clients, opened an American arm, Penn Pharmaceutical Services US, in Philadelphia.

The Mentholatum Company's best-known products, Mentholatum Deep Heating Rub, but they can probably find another of the company's bestsellers in their medicine cabinets -- Oxy Pads. The Mentholatum Company, a subsidiary of ROHTO Pharmaceutical, makes OTC products to relieve a variety of common ailments, including acne, cold sores, aches and pains, and chest congestion. In addition to the Oxy and Mentholatum brands, the firm sells its products under the WellPatch, Rohto, Fletcher's, Red Cross, Natural Ice, and Softlips monikers. ROHTO's Mentholatum companies have operations in more than a dozen countries and sells products in more than 150 countries.

Radiant Research is aglow with success. The contract research organization (CRO) conducts late phase human clinical trials for drugmakers and medical device makers at a network of some 25 research facilities that it owns across the US. Its services run the gamut from early Phase IIb trials all the way to post-approval Phase IV testing for new therapies in areas including cardiology, infectious diseases, asthma and allergies, and women's health. Radiant recruits the participants for the trials as well as gathers data for the companies; it also provides study design, consulting, and analysis services. Clients include major pharmaceutical companies, as well as biotech and medical device companies.

Biovitrum company makes pharmaceuticals that treat hemophilia and autoimmune diseases like rheumatoid arthritis, scleroderma (hardening of the skin), and others. Its available products include arthritis drug Kineret and cancer side-effect drug Kepivance. Biovitrum company also has drugs for inflammatory diseases and absorption disorders in development in its pipeline. Biovitrum distributes its products to Europe, Australia, and the US through partnerships with pharmaceutical giants like Pfizer and Amgen.

Insys Therapeutics, Inc. company focuses on developing drugs for treating side effects of chemotherapy (such as nausea), as well as therapies for pain management and other central-nervous-system conditions. Its Dronabinol HG candidate, a generic capsule form of Marinol awaiting FDA approval, may treat chemotherapy-induced nausea and vomiting. The firm is also developing inhalation and room-temperature capsule and syrup forms of Dronabinol. In addition, its Fentanyl SL spray, delivered under the tongue for quick absorption, treats pain in cancer patients. All of the company's drug candidates are unique formulations of already-approved therapeutic ingredients.

AVIVA Biosciences develops biochips to speed drug discovery and research. The chips help researchers learn how cells interact with each and their environment which in turn helps scientists to create drugs that target those behaviors. The firm is also developing a means for isolating hard-to-detect rare cells from blood samples; this technology could be used in prenatal care, such as detecting Down syndrome in the first trimester of pregnancy. It can also be used for cancer diagnostics. Chinese life sciences company, CapitalBio, is AVIVA's primary shareholder.

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