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Drug Manufacturers - Major
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Drugs - Generic

SSCI, Inc.

SSCI, Inc.

SSCI, Inc. company provides research, analytical, and consulting services to the pharmaceutical and chemical industries. For its drugmaker customers, the R&D firm offers drug formulation, stabilization, engineering services, and regulatory consulting, all which allow pharmaceutical companies to speed up the development process, which can last as long as 15 years. SSCI's analysis services include moisture and organic vapor sorption and desorption studies, thermal analysis, and micromeritics, or the characterization of the surface of a solid. SSCI is a subsidiary of pharmaceutical services firm Aptuit.

Palatin Technologies, Inc.

Palatin Technologies, Inc.

Palatin Technologies, Inc. company was founded in 1986 and is based in Cranbury, New Jersey. Palatin Technologies, Inc., a biopharmaceutical company, engages in the discovery and development of peptide, peptide mimetic, and small molecule agonist compounds with a focus on melanocortin (MC) and natriuretic peptide receptor systems in the United States. The company's products under development include PL-3994, a peptide mimetic natriuretic peptide receptor A agonist for the treatment of heart failure; Bremelanotide, a peptide melanocortin receptor agonist for the treatment of sexual dysfunction, targeting female sexual dysfunction and erectile dysfunction in patients non-responsive to current therapies; and PL-6983, a peptide melanocortin receptor agonist for the treatment of female sexual dysfunction. Its products in development also comprise melanocortin receptor-based compounds for treatment of obesity, diabetes, and related metabolic syndrome; and NeutroSpec, a radiolabeled monoclonal antibody product for imaging and diagnosing infection. Palatin Technologies, Inc. has a licensing and research collaboration agreement with AstraZeneca AB to discover, develop, and commercialize compounds that target melanocortin receptors for the treatment of obesity, diabetes, and related metabolic syndrome.

Allon Therapeutics Inc.

Allon Therapeutics Inc.

Allon Therapeutics Inc. company's primary focus is on developing treatments for Alzheimer's and other neurodegenerative diseases that lead to memory loss and cognitive impairment. Its lead candidate AL-108 is a nasal spray that has shown some efficacy in clinical trials in treating the symptoms of patients with amnestic mild cognitive impairment, a precursor to Alzheimer's. Allon has collaborations with the National Institute on Aging, the Alzheimer's Disease Cooperative Study, the Institute for the Study of Aging, and the Tel Aviv University.

Takeda San Diego, Inc.

Takeda San Diego, Inc.

Takeda San Diego develops high-throughput protein crystallography systems used to speed up the drug discovery process. The company's technology can detect the three-dimensional shape of proteins, an important step in determining how a drug can be attached to a protein to produce a therapeutic effect. The US biotech developer is one of Japanese drug maker Takeda's main research and development facilities. The subsidiary's drug discovery know-how is being used to develop new therapies for metabolic diseases such as diabetes, cancer, and inflammatory conditions.

Synta Pharmaceuticals Corp.

Synta Pharmaceuticals Corp.

Synta Pharmaceuticals Corp., a biopharmaceutical company, focuses on discovering, developing, and commercializing small molecule drugs to extend and enhance the lives of patients with severe medical conditions, including cancer and chronic inflammatory diseases. It has a global partnership with Roche for developing novel CRACM inhibitors, an oral calcium released activated calcium modulator ion channel inhibitor program that is in the lead optimization stage for the treatment of autoimmune diseases. The company also retains rights in various indications and markets to its other drug candidates and programs, which include STA-9090, an Hsp90 inhibitor that is in Phase 1 development; elesclomol, an oxidative stress inducer for the treatment of cancer; and apilimod, an oral IL-12/23 inhibitor, which is in Phase 2 for rheumatoid arthritis. In addition, Synta Pharmaceuticals Corp. is developing STA-9584, a vascular disrupting agent that is in preclinical development. The company was incorporated in 2000 and is based in Lexington, Massachusetts.

SuperGen, Inc.

SuperGen, Inc.

SuperGen was founded in 1991 and is based in Dublin, California. SuperGen, Inc., a pharmaceutical company, engages in the discovery, development, and commercialization of therapies to treat patients with cancer. The company licensed its new drug application approved product, Dacogen for the treatment of patients with myelodysplastic syndromes. It primarily focuses on developing MP-470, a DNA repair suppressor; SGI-1776, a PIM kinase inhibitor; MP-529, an Aurora kinase inhibitor; SGI-110, a DNMT1 inhibitor; and SGI-1252, a JAK2 inhibitor. SuperGen also has an approved product, Mitozytrex for the treatment of solid tumors. In addition, the company is developing Orathecin, a Phase III clinical trial product for the treatment of solid tumors; Partaject busulfan, a Phase I/II clinical trial product for neoplastic meningitis/bone marrow transplant; Partaject Orathecin, a non-clinical stage product for the treatment of solid tumors; and CZ 112, a Phase I clinical trial product for the treatment of solid tumors. It is also developing Cremophor-free paclitaxel, a non-clinical stage product for the treatment of solid tumors; Avicine, a therapeutic vaccine for the treatment of cancer, which is in Phase II trial; VEGF, a non-clinical stage product for the treatment of anti-angiogenesis; PZG, a Phase II clinical trial product for the treatment of type II diabetes; and AM454, a phosphocholine derivative, which is in non-clinical stage for obesity/diabetes. The company sells its products to clinics, hospitals, hospital buying groups, drug distributors, and wholesalers in the United States and Europe. It has a collaboration agreement with GlaxoSmithKline Inc. to discover and develop cancer therapeutics based on epigenetic targets.

China DongSheng International, Inc.

China DongSheng International, Inc.

China DongSheng International manufactures nutritional supplements and air purifiers. Founded in 1991 as PaperClip Imaging Software, the company's original business was document management software development. After a 2006 reverse merger with American Sunrise International (the holding company of China-based Jilin Dongsheng Weiye Science & Technology Development Co.), the company changed its name to China DongSheng International and shifted its focus to natural health supplements and purifiers. Now generating the majority of its revenues from its new lines, China DongSheng plans to spin off its PaperClip operations.

Perlegen Sciences, Inc.

Perlegen Sciences, Inc.

Perlegen deciphers genetic signatures. The biotech research company performs whole genome scans to help drugmakers improve drug safety and efficacy and optimize clinical trials. The company also researches the genetic causes of disease and drug response. Using DNA probe arrays from Affymetrix, which owns some 20% of the firm, Perlegen examines multiple whole genomes at a time, looking for variations (single nucleotide polymorphisms, or SNPs) that are responsible for disease. SNPs and groups of SNPs, known as haplotypes, are also responsible for the response, or lack of one, to a drug. Drugmakers hope to use this information to develop genetically targeted medicines.

Mission Pharmacal Company

Mission Pharmacal Company

Mission Pharmacal was founded in 1946 by the Walsdorf family, which still owns and runs the business. Mission Pharmacal Company makes prescription and over-the-counter (OTC) remedies for infection, kidney stones, and arthritis, and nutritional supplements. Mission's products include muscle ointment Thera-Gesic, Fosfree multivitamin supplement, kidney stone preventer Urocit-K, parasitic and bacterial infection fighter Tindamax, and CitraNatal prescription prenatal vitamins. The company also offers third-party OTC, nutritional, and prescription manufacturing, packaging, and inventory management from its Texas-based production facility.

Atrium Innovations Inc.

Atrium Innovations Inc.

Atrium Innovations (formerly Atrium Biotechnologies) believes you are what you eat. Or rather, you are what you take! The company manufactures and markets more than 1,300 vitamins, minerals, and nutritional supplements geared toward alternative health consumers. Its Pure Encapsulations line of vitamin and herbal extract capsules are a premium brand of natural hypoallergenic products. The company sells products to health care professionals in more than 35 countries, primarily in North America and Europe, through its direct sales and marketing network.

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