Indiana Botanic Gardens makes, markets, and sells herbal supplements, cosmetics, and other natural products.Its Botanic Choice and Botanic Spa lines feature such exotic ingredients as hoodia (an African desert plant), Indian Water Hyssop, and emu oil. In all, it sells about 1,700 items to customers throughout the US and abroad. The company does most of its business through its mail-order catalogue and online retail site; it also operates a retail store and offers wholesale sales for other retailers. Joseph E. Meyer, author of the classic reference book The Herbalist, founded Indiana Botanic Gardens in 1910. His great-grandson Tim Cleland is the company's president.

Bio-Botanica was founded in 1972 by CEO Frank D'Amelio. Bio-Botanica Inc. company develops and manufactures a variety of botanical extracts used by customers throughout the US and internationally, in the nutraceutical, food and beverage, and cosmetics industries. Bio-Botanica's more than 300 extracts come in solid, semi-solid, powdered, and liquid forms and are used as both active ingredients and preservatives in products ranging from teas to soaps and homeopathic remedies. The company also produces its own line of consumer products, including extracts and blended nutritional supplements, which are sold through retailers under the Nature's Answer brand.

Quintiles Transnational has plenty to CRO about. One of the world's top contract research organizations (CROs), with operations in more than 50 countries, it helps drug and medical device companies develop and sell their products. The firm provides a comprehensive range of clinical trials management services, including patient recruitment, data analysis, laboratory testing, and regulatory filing. Its consulting unit offers strategic advice at every stage of drug discovery and development, and its Innovex subsidiary is a contract sales organization providing sales personnel to promote approved products. An investment group led by founder and CEO Dennis Gillings owns the company.

DPT Laboratories will turn a discovered drug into a developed and commercialized drug. The contract manufacturing and development company makes prescription and over-the-counter drugs with an emphasis on semi-solid and liquid formulations including lotions, gels, aerosol foams, nasal sprays, and creams. It works with both conventional and biopharmaceutical compounds and can manufacture small quantities for pilots and clinical trials, and all the way up to commercial production. DPT is a subsidiary of DFB Pharmaceuticals and has manufacturing facilities in Texas and New Jersey.

Prometheus company markets several drugs that treat gastrointestinal disorders, such as irritable bowel syndrome and ulcerative colitis. Its Entocort, which it co-promotes with AstraZeneca, is a steroid that reduces the bowel inflammation associated with Crohn's disease. Prometheus Laboratories markets its products mainly to US gastroenterologists. It also pairs its drug offerings with a diagnostic testing service that helps doctors differentiate between various gastrointestinal diseases and prescribe the right Prometheus remedy; it runs all of its tests at its San Diego lab facility. Prometheus company plans to conduct an IPO.

Intervet/Schering-Plough Animal Health company develops, manufactures, and markets veterinary vaccines and pharmaceutical products. Its product portfolio includes vaccines for use in pets, livestock, poultry and aquaculture; treatment lines include antiparasitics, anti-infectives, and endocrine products. Intervet/Schering-Plough Animal Health also develops feed additives and animal productivity enhancers. Intervet/Schering-Plough Animal Health operates in more than 50 countries and sells its products around the world. Intervet/Schering-Plough Animal Health company is a subsidiary of Merck.

Boehringer Ingelheim Pharmaceuticals brings a little German drugmaking know-how to the USA. The firm is the pharmaceuticals unit of Boehringer Ingelheim Corporation, which is the US headquarters of Germany's Boehringer Ingelheim. It sells a range of prescription and over-the-counter drugs in the US market, including respiratory treatments Spiriva and Atrovent; high blood pressure medication Micardis; enlarged prostate treatment Flomax; Parkinson's disease drug Mirapex; and HIV/AIDS products Aptivus and Viramune. It is also an R&D center for Boehringer Ingelheim, specializing in immunology, inflammatory conditions, and cardiovascular disease.

DRAXIS Specialty Pharmaceuticals (formerly DRAXIS Health) lights up your insides with its own radiopharmaceuticals, but its main business is making other drug companies' injectable drugs, lotions and pills. The company's larger DRAXIS Pharma unit is a contract manufacturer specializing in liquid and freeze-dried injectable drugs, though it also makes sterile and non-sterile ointments, creams, and other formulations. Another unit, DRAXIMAGE, develops and makes radiopharmaceuticals, such as radioactive iodine, for use in diagnostic and therapeutic nuclear medicine procedures. DRAXIMAGE sells its products mostly in the US and Canada. In 2008 India-based Jubilant Organosys acquired DRAXIS for about $255 million.

Herborium Group is a developer and marketer of herbal nutritional supplements. Herborium's product line includes Traditional Chinese Medicine herbal blends designed to clear up acne (AcnEase), boost energy (Energy Restoration), and heighten sexual performance (Lasting Pleasure for women, MaleForce for men). Herborium sells it products in the US, the UK, and continental Europe through a network of distributors, specialty retailers, such as natural foods stores, and online marketplaces. The company's founder, president and CEO Agnes Olszewski and director James Gilligan hold about 70% of the company's shares.

ChemoCentryx is focused exclusively on the discovery, development and commercialization of orally-administered small molecule therapeutics that target chemokine receptors and related chemoattractant receptors. Since its founding, ChemoCentryx has established one of the broadest pipelines of chemokine-based therapeutics in the pharmaceutical industry. This has been based on our pioneering insight into the chemokine system, a complex network of chemokine (CHEMO-attractant cytoKINE) molecules (ligands) and receptors that work together to regulate the movement of immune cells in and out of inflamed tissues. Each of our novel small molecule product candidates is designed to target a specific chemokine or chemoattractant receptor, thereby blocking the inappropriate immune system cascade underlying a given disease.

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