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Drug Manufacturers - Major
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Drugs - Generic

Palatin Technologies, Inc.

Palatin Technologies, Inc.

Palatin Technologies, Inc. company was founded in 1986 and is based in Cranbury, New Jersey. Palatin Technologies, Inc., a biopharmaceutical company, engages in the discovery and development of peptide, peptide mimetic, and small molecule agonist compounds with a focus on melanocortin (MC) and natriuretic peptide receptor systems in the United States. The company's products under development include PL-3994, a peptide mimetic natriuretic peptide receptor A agonist for the treatment of heart failure; Bremelanotide, a peptide melanocortin receptor agonist for the treatment of sexual dysfunction, targeting female sexual dysfunction and erectile dysfunction in patients non-responsive to current therapies; and PL-6983, a peptide melanocortin receptor agonist for the treatment of female sexual dysfunction. Its products in development also comprise melanocortin receptor-based compounds for treatment of obesity, diabetes, and related metabolic syndrome; and NeutroSpec, a radiolabeled monoclonal antibody product for imaging and diagnosing infection. Palatin Technologies, Inc. has a licensing and research collaboration agreement with AstraZeneca AB to discover, develop, and commercialize compounds that target melanocortin receptors for the treatment of obesity, diabetes, and related metabolic syndrome.

Omeros Corporation

Omeros Corporation

meros Corporation was founded in 1994 and is based in Seattle, Washington. Omeros Corporation is a clinical-stage biopharmaceutical company engaged in discovering, developing and commercializing products focused on inflammation and disorders of the central nervous system. The Company’s clinically advanced product candidates are derived from its PharmacoSurgerytm platform designed to improve the clinical outcomes of patients undergoing arthroscopic, ophthalmological, urological and other surgical and medical procedures. Its PharmacoSurgery platform is based on low-dose combinations of therapeutic agents delivered directly to the surgical site throughout the duration of the procedure to preemptively inhibit inflammation and other problems caused by surgical trauma and to provide clinical benefits both during and after surgery.

Althea Technologies, Inc.

Althea Technologies, Inc.

Althea Technologies provides services that help drug developers speed up the drug discovery and testing process, as well as reduce risks and costs associated with research and development efforts. Founded in 1998 by co-chairs Francois Ferre and Magda Marquet -- who hold Ph.D.s in molecular oncology and biochemical engineering -- the company assists in the development process from discovery through testing, regulatory support, and contract manufacturing stages. Services include gene expression analysis, protein production, and therapeutic and vaccine product manufacturing for clinical trials.

ReGen Therapeutics Plc

ReGen Therapeutics Plc

ReGen Therapeutics did. Its main product is Colostrinin, a polypeptide derived from ovine and bovine colostrum (the first milk produced after the birth of an offspring). The company developed a nutraceutical version of the product that its licensee Metagenics launched in the US under the name CogniSure in 2007. ReGen continues development of a pharmaceutical preparation, as well as a veterinary nutraceutical version for pets. In addition to Colostrinin, ReGen is developing existing insomnia drug Zolpidem as a treatment for head trauma victims. The company's Guildford Clinical Pharmacology subsidiary is a UK-based contract research organization.

Trius Therapeutics, Inc.

Trius Therapeutics, Inc.

Trius Therapeutics is an early-stage biopharmaceutical company developing antibiotics to treat life-threatening bacterial infections. Torezolid phosphate, its most important drug in development, is an IV- and orally-administered antibiotic with a potential to treat antibiotic-resistant strains of staph infections, known as MRSA (methicillin-resistant Staphylococcus aureus). Until the company is able to sell torezolid phosphate to hospitals and other health care providers, the company is primarily funded by government grants, research contracts, and collaboration agreements. The company filed for an initial public offering in November 2009.

Mirus Bio Corporation

Mirus Bio Corporation

Mirus Bio provides gene transfer technologies to the pharmaceutical industry. The company's reagent kits assist researchers with in vitro transfection, in vivo delivery, DNA and RNA labeling, and RNA interference. Besides its kits, Mirus Bio is also developing its own therapies based on its intravenous technology, called Pathway IV, that facilitates the delivery of plasmid DNA to targeted muscles. One of those therapies is MyoDys, a gene therapy designed to treat muscular dystrophy by delaying loss of muscle function. Mirus Bio is also developing treatments for peripheral ischemia and anemia. Mirus Bio has agreed to be acquired by Roche Holding for $125 million.

Orbus Pharma Inc.

Orbus Pharma Inc.

Orbus Pharma offers pharmaceutical research, manufacturing, packaging, and warehousing services on a contract basis for other drug companies. Orbus Pharma specializes in oral suspension and generic pharmaceutical products. The company serves the North American, European, and other international markets. It develops formulations of existing drugs using proprietary delivery systems and then provides out-licensing and contract manufacturing services for the products. Orbus has agreed to allow China-based pharmaceutical firm Nanjing Sanhome Pharmaceutical Co. to acquire a majority of its shares.

Kendle International Inc.

Kendle International Inc.

Kendle International Inc. was founded in 1981 and is based in Cincinnati, Ohio. Kendle International Inc. is a global clinical research organization (CRO) that provides a range of Phase I-IV global clinical development services to the biopharmaceutical industry. The Company augments the research and development activities of biopharmaceutical companies by offering clinical research services and information technology designed to reduce drug development time and expense. Kendle International Inc. is managed in two reportable segments: Early Stage and Late Stage. The Early Stage business focuses on the Company’s Phase I operations while Late Stage is comprised of clinical development services related to Phase II through III clinical trials conducted worldwide, late phase clinical development services related to Phase IIIB and IV clinical trials conducted worldwide, regulatory affairs and biometrics offerings. In June 2008, the Company announced the acquisition of DecisionLine Clinical Research Corporation.

Biovitrum AB (publ)

Biovitrum AB (publ)

Biovitrum company makes pharmaceuticals that treat hemophilia and autoimmune diseases like rheumatoid arthritis, scleroderma (hardening of the skin), and others. Its available products include arthritis drug Kineret and cancer side-effect drug Kepivance. Biovitrum company also has drugs for inflammatory diseases and absorption disorders in development in its pipeline. Biovitrum distributes its products to Europe, Australia, and the US through partnerships with pharmaceutical giants like Pfizer and Amgen.

ReNew Life Formulas, Inc.

ReNew Life Formulas, Inc.

ReNew Life Formulas, Inc. was founded by President Brenda Watson in 1997. ReNew Life Formulas aims to make a clean sweep of clogged colons and hasten one's pace to the restroom. ReNew Life Formulas company makes and wholesales dietary supplements and therapeutic products for digestive health. Its products CleanseSMART, ParaGONE, CandiGONE, and Liver Detox are a few of the products offered as part of its cleansing and detoxification line. Its digestive support products include fish oils, probiotics, and digestive enzymes. The company also makes products tailored for kids. ReNew Life Formulas sells its products through health food stores and online retailers in the US and Canada.

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