Arrow Therapeutics was founded in 1998; AstraZeneca acquired the firm in 2007. Arrow Therapeutics is a pharmaceutical product discovery company that is researching new anti-infective medicines. The company's top candidate is RSV604, an antiviral molecular program to combat respiratory syncytial virus (RSV), a leading cause of respiratory infections worldwide. This candidate is currently undergoing clinical trials and has been licensed to Novartis. Other leading programs include compounds developed to fight infectious dieseases such as Hepatitis C, herpes, and chicken pox.

Virbac Corporation makes animal health and pet-care products and sells them to veterinarians and retailers. For dogs and cats it makes C.E.T dental products, Allederm dermatological products, and digestive and hairball remedies. The company's Iverhart medication prevents heartworms in dogs. Virbac also makes antibiotics, dewormer, and euthanasia products. Its other brands include Biomox, Clintabs, and Vetasyl. In addition to producing its own animal health products, the company provides contract manufacturing through subsidiary PM Resources. The company is owned by Virbac SA.

Mirus Bio provides gene transfer technologies to the pharmaceutical industry. The company's reagent kits assist researchers with in vitro transfection, in vivo delivery, DNA and RNA labeling, and RNA interference. Besides its kits, Mirus Bio is also developing its own therapies based on its intravenous technology, called Pathway IV, that facilitates the delivery of plasmid DNA to targeted muscles. One of those therapies is MyoDys, a gene therapy designed to treat muscular dystrophy by delaying loss of muscle function. Mirus Bio is also developing treatments for peripheral ischemia and anemia. Mirus Bio has agreed to be acquired by Roche Holding for $125 million.

Tekmira Pharmaceuticals is giving diseases the silent treatment. The biopharmaceutical company is attempting to develop therapies that inhibit or "silence" certain disease-causing genes through ribonucleic acid interference (RNAi), a mechanism that disrupts the production of proteins that can lead to cancer, metabolic, and infectious diseases. Tekmira's lead candidates are being developed to treat tumors and high cholesterol. It also partners with other pharmaceutical companies, such as Alnylam Pharmaceuticals and Roche, to advance additional RNAi products using Tekmira's stable nucleic acid-lipid particles (SNALP) RNAi drug delivery technology.

Endocyte, Inc. company was founded in 1996 and is based in West Lafayette, Indiana. Endocyte, Inc., a biopharmaceutical company, develops receptor-targeted therapeutics to treat cancer and autoimmune/inflammatory diseases. The company provides EC17, a folate-targeted hapten therapy drug to treat metastatic renal and ovarian cancer; EC145, a folate-targeted chemotherapeutic conjugate to treat various tumors, including cancers of the breast, lung, and blood; EC0225, a targeted chemotherapy drug; BMS753493, a folate-targeted anti-cancer therapy drug; EC0434 to target folate receptor positive tumors; and EC0305, an anti-cancer therapy drug. It also offers EC0286, a folate-targeted small molecule for the treatment of inflammatory diseases; and EC20, a folate-targeted radiopharmaceutical imaging agent to identify folate-receptor positive cancers.

Santa Cruz, California might be known for its sun-baked bodies; Santa Cruz Biotechnology is known for its antibodies. The company makes antibodies used by researchers to identify and treat a variety of conditions. Its products include growth factor antibodies, steroid receptor antibodies, and tumor suppressor antibodies. The company also offers more than 10,000 target-specific small interfering RNA (siRNA), which are used to silence genes. Its siRNAs are designed to silence tumors suppressor proteins, cell cycle proteins, and lymphocyte signaling proteins, among others. Santa Cruz Biotechnology has offices in California, Japan, and Germany and sells its products through distributors worldwide.

Osiris Therapeutics, Inc. company was founded in 1992 and is headquartered in Columbia, Maryland. Osiris Therapeutics, Inc., a stem cell therapeutic company, develops products to treat medical conditions in the inflammatory, orthopedic, and cardiovascular areas in the United States. The company's principal product includes Prochymal, which is in phase III clinical trials for the treatment of steroid refractory Graft versus Host Disease (GvHD), acute GvHD, Crohn's disease, and acute radiation syndrome; and in phase II clinical trials for the treatment of Type I diabetes mellitus, acute myocardial infarction, and chronic obstructive pulmonary disease. Its product also consists of Chondrogen, a Phase II clinical trial product for the treatment of osteoarthritis and the reduction of pain in the knee. Osiris Therapeutics has collaboration agreements with Genzyme Corporation for the development and commercialization of Prochymal and Chondrogen; Juvenile Diabetes Research Foundation for the development of Prochymal as a treatment for the preservation of insulin production in patients with newly diagnosed type 1 diabetes; and JCR Pharmaceuticals Co., Ltd. for distributing Prochymal for the treatment of GvHD in Japan.

Vical Incorporated was founded in 1987 and is based in San Diego, California. Vical Incorporated researches and develops biopharmaceutical products based on its deoxyribonucleic acid (DNA) delivery technologies for the prevention and treatment of serious or life-threatening diseases. The Company has three active independent development programs in the areas of infectious disease and cancer. These are a Phase III clinical trial using its Allovectin-7 immunotherapeutic in patients with metastatic melanoma; a Phase II clinical trial using its cytomegalovirus (CMV) DNA vaccine in hematopoietic cell transplant patients, and a Phase I clinical trial using its H5N1 pandemic influenza DNA vaccine formulated with its Vaxfectin adjuvant.

Corgenix Medical Corporation company was founded in 1985 and is headquartered in Broomfield, Colorado. Corgenix Medical Corporation, together with its subsidiaries, engages in the research, development, manufacture, and marketing of in vitro diagnostic products for use in disease detection and prevention in the United States and internationally. The company offers autoimmune disease products that are used for the diagnosis and monitoring of autoimmune diseases, including RA, SLE, mixed connective tissue diseases, Sjogren’s Syndrome, Dermatopolymyositis, and Scleroderma; and antiphospholipid antibody testing products, which are used in the diagnosis of clotting and bleeding disorders, including von Willebrand's disease. It also provides AspirinWorks, a urine test kit that measures an individual's response to aspirin dosage and allows physicians to adjust the dosage or recommend alternative therapy; and liver disease products, which include hyaluronic acid, a component of the matrix of connective tissues found in synovial fluid of the joints where it acts as a lubricant and for water retention. The company sells its products to hospitals, clinical testing laboratories, universities, biotechnology and pharmaceutical companies, and research institutions. It markets its products through a network of sales representatives, distributors, and private label agreements.

Hyaluron, Inc. company specializes in aseptically filling syinges and vials with liquid and lyophilized (treated for preservation) products serving the medical and pharmaceutical markets. Hyaluron manufacturing facility can accomodate the needs of clients small and large, from pre-clincial batches to commercial scale development. Hyaluron's expertise also extends into scaling up formulations such as emulsions, viscous gels, suspensions, liposomes, and proteins which will eventually fill the vials and syringes of the company's clients. The company can fill about 150,000 syringes a day and 75,000 vials.

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