Orbus Pharma offers pharmaceutical research, manufacturing, packaging, and warehousing services on a contract basis for other drug companies. Orbus Pharma specializes in oral suspension and generic pharmaceutical products. The company serves the North American, European, and other international markets. It develops formulations of existing drugs using proprietary delivery systems and then provides out-licensing and contract manufacturing services for the products. Orbus has agreed to allow China-based pharmaceutical firm Nanjing Sanhome Pharmaceutical Co. to acquire a majority of its shares.

Vion Pharmaceuticals was founded in 1992 and is based in New Haven, Connecticut. On December 17, 2009, Vion Pharmaceuticals, Inc. filed a voluntary petition for reorganization under Chapter 11 in the U.S. Bankruptcy Court for the District of Delaware. Vion Pharmaceuticals, Inc., a development-stage pharmaceutical company, develops and commercializes therapeutics for the treatment of cancer. It has two agents in clinical trials, Onrigin and Triapine. Onrigin, a novel alkylating agent that damages DNA to prevent cancer cells from reproducing, is in various clinical trials for the treatment of various indications, such as acute myeloid leukemia (AML), relapsed AML, de novo poor-risk, small cell lung cancer, brain tumors, myelodysplastic syndromes, chronic lymphocytic leukemia, hematologic malignancies, and solid tumors. Triapine is a small molecule in various clinical trials to prevent the replication of tumor cells by blocking a critical step in DNA synthesis. Vion company's other products and product candidates include MELASYN, a water-soluble, synthetic version of melanin for formulation of skin care products and cosmetics; and Nucleoside Analogs, known as elvucitabine, which is in Phase II clinical trials as an antiviral drug for the treatment of human immunodeficiency virus.

Celsis International plc company was founded in 1992. Celsis International is all about playing it safe. Through the company's Product Group, it makes rapid diagnostic and monitoring systems used to detect and measure microbial contamination in consumer products and food. Its RapidScreen assays are used by makers of personal care goods, cosmetics, OTC drugs, and a variety of beverages. CellScan Innovate is used by dairy producers. The division, which accounts for little more than half of Celsis International's sales, counts among its customers Dow Corning and Gillette. Celsis Laboratory Group performs quality testing for the cosmetics, drug, and chemicals industries.

BioFocus DPI takes the guesswork out of your drug discovery. The UK-based company specializes in pre-clinical drug discovery services, assay development and screening, and compound management (including storage and delivery). The company's major clients include Pfizer, Procter & Gamble, and GlaxoSmithKline. BioFocus was founded by a group of Wellcome scientists in 1997, and about a decade later was acquired by Galapagos. It now operates as that company's services division. Formerly known as BioFocus, the firm added DPI to its name after Galapagos acquired the drug discovery business of Discovery Partners International and merged it with existing BioFocus operations.

Genetix Group plc, along with its subsidiaries, is engaged in the design, development, manufacture and marketing of automated systems, services and consumables for cell biology, cytogenetics, pathology, proteomic and genomic research worldwide. The biopharmaceutical family of products include the ClonePixFL and associated reagents, which are used to identify the antibody clones that form the basis of pharmaceutical drugs. The ClonePix FL is also used to identify high-yielding cell lines for a customer’s production process. Its Cytovision systems are used worldwide for both pre and post natal genetic testing, and identifying certain forms of cancer, such as leukemia. Its Ariol system is used to image tissue samples from patients. Its wholly owned subsidiaries include Genetix Limited, Genescreen Limited, Genpak Limited, Genetix GmbH and Genetix KK. In April 2009, the Company acquired SlidePath Limited. In January 2010, Danaher Corporation acquired 97% interest in the Company.

AVEO Pharmaceuticals' models don't pout, strut, or even turn heads -- unless you're a cancer drug researcher. The biotech firm develops cancer models to uncover how genes mutate into tumors and how tumors progress through additional mutations. AVEO then builds genetic profiles of such tumors and applies them to antibody (protein) drug candidates in preclinical and clinical development to help predict actual human responses. In addition to its own pipeline of potential drugs, AVEO has partnered with other pharmaceutical developers to apply its Human Response Platform to their drug candidates.

Owners (and spouses) Tei Fu Chen and Oi-Lin Chen started Sunrider International in 1982. Sunrider Corporation has blended bits of traditional Chinese herbal medicine with modern multilevel marketing. The company sells health, beauty, food, and household products enhanced with herbs and herbal extracts. Its brands include Kandesn, Vitalite, SunBright, and SunSmile. Sunrider has manufacturing operations in China, Singapore, Taiwan, and the US. Its products are sold in more than 40 countries through multilevel marketing via distributors and directly to customers. In China, its products are sold in thousands of franchised stores to avoid regulations on direct-selling. It plans to copy that model in Japan.

Otsuka Pharmaceutical Co. (OPC) is a manufacturer and distributor of pharmaceuticals, clinical testing and medical equipment, and food products. The company operates six business segments specializing in branded prescriptions, over-the-counter drugs, clinical nutritionals, diagnostic substances and devices, nutraceuticals, and skin care products ("cosmedics"). OPC's medicinal products include Mikelan eye drops for glaucoma treatment and Pletaal anti-platelet treatment. The company's line of nutraceutical consumer health products include FIBE-MINI dietary fiber supplement, Calorie Mate foods, and Pocari Sweat sports drink. Otsuka Pharmaceutical is part of the very diverse Otsuka Group.

Henderson Morley takes aim at those pesky microscopic parasites we know as viruses. The company researches and develops vaccines and treatments for viral infections by preventing them from replicating once they invade their host cells. One of its lead product candidates is a vaccine for genital herpes that could be used as a preventative or a therapeutic measure. Other candidates target human cytomegalovirus and human papillomavirus. Instead of taking its candidates through all phases of development, Henderson Morley instead looks to out-license its candidates. Chairman Andrew Knight owns 34% of the company.

POZEN, Inc. was founded in 1996 and is headquartered in Chapel Hill, North Carolina. POZEN, Inc. engages in the development of pharmaceutical products for the treatment of acute and chronic pain, and other pain-related conditions. The company has development and commercialization alliances with GlaxoSmithKline for Treximet, which is used for the acute treatment of migraine attacks with or without aura in adults; and AstraZeneca for proprietary fixed dose combinations of naproxen with the proton pump inhibitor esomeprazole magnesium in a single tablet for conditions, such as osteoarthritis and rheumatoid arthritis in patients who are at risk for developing non-steroidal anti-inflammatory drug-associated gastric ulcers.

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