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Trinity Mother Frances Health System Foundation (dba Trinity Mother Frances Hospitals and Clinics) has a simple mission: to improve patient health. Consisting of two hospitals, several specialist facilities, and a large physicians' group, Trinity Mother Frances serves northeastern Texas. Its largest acute-care facility is Mother Frances Hospital-Tyler with more than 390 beds, offering comprehensive medical, surgical, trauma, and cardiovascular care. The smaller Mother Frances Hospital-Jacksonville facility provides emergency, diagnostic, pediatric, and women's health services. The Trinity Clinic is a multi-specialty physician group that includes some 250 doctors in about 40 community clinics.

Trover Health System (formerly Trover Foundation) provides health care services to residents of western Kentucky through its Regional Medical Center, a general hospital with more than 400 beds, and nine Trover Clinic locations with some 100 physicians on staff. Regional Medical Center provides specialized services such as home health care, nephrology, rehabilitation, and trauma care. Trover Health's physicians represent about 40 specialties to residents in an area covering six counties. Its centers of excellence include the Merle M. Mahr Cancer Center, the Center for Women's Health, the Center for Heart and Vascular Services.

Truman Medical Center (TMC) provides primary and mental health care at two not-for-profit hospitals in the Kansas City (Missouri) area with a combined total of about 350 beds. Its Hospital Hill runs one of the busiest emergency rooms in Kansas City (serving about 80,000 patients annually) and is known for treatments related to asthma, diabetes, obstetrics, ophthalmology, weight management, and women's health. TMC Lakewood is a leading academic medical center providing a range of health care services to the greater Kansas City metropolitan area, including uninsured patients.

Twin County Regional Healthcare provides a variety of medical services to residents in Virginia. Its hospital offers specialized services such as emergency medicine, obstetrics, rehabilitation, and cardiac care. The health care center, which has more than 140 beds, also provides home health and hospice services, as well as wellness and behavioral health centers. Its emergency department treats some 16,300 patients each year.

UC Health is Cincinnati's scholarly health care provider. The medical provider, formerly known as The Health Alliance of Greater Cincinnati, is a partnership between the University of Cincinnati, University Hospital, and the University of Cincinnati Physicians. Additionally, UC Health is home to the West Chester Medical Center (a full-service community hospital), the Drake Center rehabilitation hospital, and the UC Health Surgical Hospital. Another physician practice group, UC Health Primary Care (formerly Alliance Primary Care), operates general practice locations. UC Health was formed in 1994 and originally included five hospitals.

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