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Focusing on orthopedics, wound care, and endoscopy, the firm makes products to repair joints, skin, soft tissue, and bone. Smith & Nephew plc orthopedics division makes hip, knee, and shoulder replacements, in addition to fixation and bone-growth devices used to repair broken bones. Smith & Nephew also makes arthroscopes, blades, digital cameras, and other surgical products through its endoscopy division. Its advanced wound management division manufactures and sells bandages and dressings used to treat a variety of injuries. The company operates in more than 30 countries worldwide.

Smiths Medical provides the tools doctors need in intensive care, surgery, and post-operative care. The company develops medical devices for treatment in areas such as cardiology, oncology, pain management, and home health care. Products include general anesthesia devices, epidural components, safety lancets, and pulse monitors, as well as a line of assisted reproduction products. Smiths Medical provides its products to hospitals (which make up the majority of its customer base), specialists, and home care providers. Most of its worldwide territories are serviced through wholly-owned local sales and distribution companies. A division of the Smiths Group, the company is led by president Srini Seshadri.

Solta Medical (formerly Thermage) makes a non-invasive skin-tightening system that uses radiofrequency energy to get rid of pesky wrinkles on the face and hands, around the eyes, and on other creased and crumpled body parts. The company markets its Thermage ThermaCool radiofrequency generators and single-use ThermaTips to plastic surgeons, dermatologists, and other doctors around the world. Solta also sells Fraxel skin resurfacing systems. It uses a direct sales force in the US and a network of distributors in more than 80 countries for international sales.

Somanetics sells the INVOS System, a noninvasive device that monitors blood oxygen levels in the brain, primarily during surgery. Based on Somanetics' in vivo optical spectroscopy (INVOS) technology, the device's disposable SomaSensors and Oxyalert sensors attach to each side of the patient's forehead, and the firm's proprietary software displays oxygen levels on a computer screen. The company sells the INVOS System through a direct sales force in the US and through distributors abroad such as Covidien and Edwards Lifesciences. The company is a wholly owned subsidiary of Covidien.

By developing, manufacturing, and marketing hearing protection products, Sonomax Technologies, wants to lower the incidence of noise-induced hearing loss (NIHL) to nil. The company sells its custom-fit earpieces as workplace safety devices and also puts its technology to work elsewhere filtering sounds in hearing aids, military headsets, and music earbuds. The company sells directly and through distributors in Canada, through distributors only in the US, and through licensees elsewhere. The Montreal-based company is led by CEO Nick Laperie.

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