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MacKay Life Sciences (formerly Biofield) is trying to blaze a trail in the diagnostic equipment market with its Biofield Diagnostic System, which employs single-use sensors to detect and examine changes associated with breast cancer. The system is based on the theory that epithelial cancers are characterized by changes in the electrical charge of the affected tissue; the sensors analyze these changes and identify if a lesion is malignant or benign. The process requires less than 20 minutes, and has possible applications to cancers of the ovaries, skin, prostate, and colon. Director James MacKay, through the MacKay Group, owns a majority interest in MacKay Life Sciences.

MAKO Surgical Corp. developed and markets the MAKOplasty partial knee resurfacing system, a minimally invasive alternative to traditional knee replacement surgery for patients with early- to mid-stage osteoarthritis. Proprietary components of the system consist of visualization technology and a robotic arm (RIO) that help orthopedic surgeons prepare the knee joint for insertion of MAKO's resurfacing implants (RESTORIS) through a small incision. With marketing approval in the US and Europe, MAKO Surgical markets to hospitals and surgeons via a direct sales force and independent orthopedic product agents and distributors.

Mammatech Corporation wants to help doctors, clinicians, moms, and other women keep an eye on breast cancer. The company manufactures a breast tumor detection training system designed to increase early detection of breast cancer and thus reduce patient deaths from the disease. Using models of a human female breast, the MammaCare System trains individuals to perform manual breast exams to detect tumors. The system comes in different interactive training packages targeting medical professionals and individuals, including those who are hearing or vision impaired. The company started as a research project in 1974 with support from the National Cancer Institute.

Maquet strives to ensure optimal surgeon performance. Maquet makes what could be some of the most crucial modern components of hospital operating theaters and post-op care facilities. The company is organized into three divisions: surgical workplaces (operating tables, surgical lights, ceiling service lights, and prefabricated operating and intensive care suites); cardiovascular (beating heart positioners, pumps, oxygenators, and grafts for open-heart and vascular surgeries); and critical care (anesthesia and ventilation systems for the operating theater and intensive care). Additionally the company provides software, disposables, and maintenance services. Maquet is a subsidiary of Getinge AB.

As important as the blood running through your veins is the oxygen it carries. Masimo knows that and makes tools that monitor arterial blood-oxygen saturation levels and pulse rates in patients. The company's product range, which is based on Signal Extraction Technology (SET), offers pulse oximeters in both handheld and stand-alone (bedside) form. Product benefits include the provision of real-time information and elimination of signal interference, such as patient movements. The company primarily markets its products globally through direct-sales representatives and distributors. It also licenses SET-based products to dozens of medical equipment manufacturers, including CareFusion, Medtronic, and Welch Allyn.

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