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You can spin a disc, or burn a disc, but when you blow a disc in your back the fun stops, and Amedica steps in. The company develops, manufactures, and commercializes joint and spine implants made of silicon nitride ceramic, a material thought to be more durable, resistant, and patient-compatible than traditional implant materials. Amedica's lead product candidates are its Valeo spinal implants which are intended to restore and maintain vertebrae alignment in the neck and lower back. Valeo spinal spacer implants have received FDA and EU approval for use as vertebra replacements. The company's other candidates include ceramic hip and knee implants with material that mimic the porous structure of natural bone.

American Medical Alert Corp (AMAC) provides health care communication and monitoring services. The company's Health Safety and Monitoring Services (HSMS) unit markets remote patient monitoring systems, including personal emergency response systems, health management and medication management systems, and safety monitoring systems. Its Telephony Based Communication Services (TBCS) unit provides telephone answering services and operates clinical trial recruitment call centers. Products are sold to consumers as well as health care facilities, such as home care, hospice, pharmacy, managed care, and other health care organizations.

American Medical Systems (AMS) aims to make life better for millions of patients afflicted with pelvic disorders. A leading maker of urological devices, AMS makes erectile dysfunction products such as inflatable penile implants, as well as urinary incontinence devices for men and women. Its other products treat such conditions as menorrhagia (excessive uterine bleeding), enlarged prostate, and fecal incontinence. AMS has around 70 independent distributors in addition to a global sale and marketing force of about 500 employees. Marketing efforts target urologists, gynecologists, colorectal surgeons, and other specialty physicians.

Amigo Mobility International proves itself a friend to the elderly and disabled with its electric wheelchairs and scooters. The company makes more than a dozen different models of motorized mobility devices, including travel scooters (which are light-weight and can be disassembled) and plus-sized scooters for large or tall customers. It also makes vehicle lifts that transfer a scooter into a car or van, as well as shopping cart-scooter combos that grocery stores and other large retail outlets purchase for the use of their disabled patrons. Amigo Mobility sells its products through dealerships across the US and abroad. Company president Al Thieme invented the first Amigo scooter in 1968.

Angiotech Pharmaceuticals is teaching old devices new tricks. The firm develops medical products that combine devices with drugs to make them more effective with fewer side effects. Its flagship product in the Pharmaceutical Technologies segment is the TAXUS drug-eluting stent, which Boston Scientific sells and for which it pays Angiotech royalties. The stent is used to open up diseased arteries, and the drug coating keeps scar tissue from forming and creating a new blockage. The company's Medical Products segment makes the Quill wound closure system and other single-use medical products for interventional radiology, ophthalmology, and surgery. Angiotech has facilities in North America and Europe.

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