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Senetek PLC (Senetek) is a life sciences company engaged in the development of technologies that target the science of healthy aging. The Company’s business consists of two business segments: dermatological/skincare compounds principally addressing photoaging and other skincare needs (Skincare), and pharmaceuticals, principally those addressing sales of monoclonal antibodies, sexual dysfunction and drug delivery of liquid injectable products (automatic injectors) (Pharmaceutical). The Skincare segment’s products include Pyratine-6, 4HBAP and Kinetin. The Pharmaceutical segment’s products include Invicorp, Reliaject, and diagnostic monoclonal antibodies used in Alzheimer’s and other disease research, which the Company licenses from Research Foundation for Mental Hygiene (RFMH) and sells to Covance Antibody Services Inc. The Company has three wholly owned subsidiaries, Senetek Drug Delivery Technologies Inc. (SSDT), Carme Cosmeceutical Sciences Inc. (CCSI) and Senetek Denmark ApS.

Sepracor Inc. company focuses its drug development efforts in two main therapeutic categories: respiratory and central nervous system (CNS) disorders. Its marketed products include asthma drug Xopenex, insomnia therapy Lunesta, and chronic obstructive pulmonary disease (COPD) treatment Brovana. Sepracor markets its products to primary care physicians and some specialists in the US; it also has some limited operations in Canada. It has licensed international development and commercialization rights for Lunesta to Eisai and GlaxoSmithKline. Sepracor was acquired for $2.6 billion by Japanese firm Dainippon Sumitomo Pharma in 2009.

Shanghai Pharmaceutical Group, or SPGC, knows that Big Pharma is big business. One of China's largest pharmaceutical companies, SPGC makes over-the-counter (OTC) medicines, prescription drugs, active pharmaceutical ingredients (APIs), biopharmaceuticals, and traditional Chinese medicine. The vertically-integrated company distributes its wares and owns more than 1,000 retail locations. SPGC sells drugs in 30 countries from five foreign offices. Its R&D facility, Central Research Institute, operates 10 centers across China. In 1996 many small producers, including Sine, Dragon & Tiger, and Pioneer, merged to form SPGC.

Shionogi & Co. wants to kill it like a shinobi (i.e. ninja) in the night. The Japanese drug firm is a leading maker of antibiotics in its home country, with a full lineup of oral and injectable anti-infectives. It has been expanding its pipeline and its portfolio of marketed products to encompass other therapeutic areas as well, with programs in metabolic conditions and pain management. Through partnerships with large global firms, it owns Japanese market rights to some big name drugs, including AstraZeneca's blood pressure drug Crestor (which Shionogi helped develop); Purdue Pharma's pain therapy OxyContin; and Merck & Co. allergy medication Claritin.

Shionogi Pharma, Inc. company was founded in 1992 and is headquartered in Atlanta, Georgia. Sciele Pharma Inc. operates as a subsidiary of Shionogi & Co. Ltd. Sciele Pharma Inc., a pharmaceutical company, engages in acquiring, developing, marketing, and selling prescription products for patients primarily in the United States. It offers oral suspensions, tablets, and capsules, as well as products prescribed by the primary care physicians. The company provides cardiovascular and diabetes products that treat patients with high cholesterol, hypertension, high triglycerides, unstable angina, and Type 2 diabetes; pediatrics products, which treat allergies, asthma, cough and cold, and attention deficit and hyperactivity disorders; and products for the health and well-being of women, as well as for mothers and their babies. It develops glycopyrrolate oral solution, a treatment for chronic, moderate-to-severe drooling in pediatric patients.

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