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VASAMED, Inc. designs, licenses, manufactures, and distributes noninvasive hemodynamic technologies for vascular, wound care, cardiovascular, and emergency medicine diagnostics. Its products include skin perfusion pressure systems and non-invasive cardiac output monitors. The company offers AcQtrac System that uses thoracic impedance cardiography to present a Cardiovasculogram waveform, which illustrates the mechanical function of the cardiovascular system, as well as used against congestive heart failure, hypertension, dystrophies requiring a pacemaker, and titrating therapies. It also offers SensiLase System, which allows physicians to assess micro-and macro circulation, as well as provides a combination of skin perfusion pressure and pulse volume recording tests that are useful in managing chronic wounds and other types of symptoms. The SensiLase System’s applications include assessing wound healing potential; monitoring pre/post-therapy, such as surgery and compression; arterial reconstruction planning and post-procedure monitoring; determining the optimal amputation level; amputation planning and post-procedure monitoring; and assisting in the diagnosis of peripheral arterial disease, critical limb ischemia, and other microcirculatory derangements. VASAMED, Inc. serves customers worldwide. The company has a patent license agreement with the Institute of Critical Care Medicine. It was formerly known as Optical Sensors Incorporated and changed its name to VASAMED, Inc. in June 2007. The company was founded in 1988 and is headquartered in Eden Prairie, Minnesota.

Vasomedical's noninvasive treatments for angina and congestive heart failure get patients' blood pumping. The company's main product is the EECP (enhanced external counterpulsation) system, which is also approved to treat coronary artery disease and cardiogenic shock. During the company's Medicare-covered treatments, cuffs attached to the patient's calves and thighs inflate and deflate in sync with the patient's heartbeat, increasing and decreasing aortic blood pressure. After about 35 treatments, patients may experience years of symptomatic relief. Vasomedical sells the system to hospitals, clinics, and other health care providers worldwide through a direct sales force and independent distributors.

Ventana Medical Systems wants to be a window into the cause of cancer. The company's slide staining systems (sold under the names BenchMark, NexES, and Symphony) are used to automate the processing and microscopic analysis of human tissue for the detection and treatment of cancer and infectious diseases. Ventana also sells consumables such as reagents and slides needed to operate the systems. It uses a direct sales force to market its products to hospital, anatomical pathology, and drug discovery labs around the globe. Its products are used by many cancer research centers, including the Mayo Clinic and Johns Hopkins Hospital. The firm is led by CEO Hany Massarany and owned by Roche.

Vision-Sciences, Inc. designs, develops, manufactures, and markets products for endoscopy. The company operates through two segments, Medical and Industrial. The Medical segment designs, manufactures, and sells a line of endoscopy-based products, including flexible endoscopes and sheath or EndoSheath disposables primarily to the ENT, urology, gastroenterology, and pulmonology markets. The Industrial segment designs, manufactures, and markets flexible borescopes under the Machida brand name. This segment offers various products, such as modulars, slim levers, knobs, battery operated portable flexible borescopes, industrial videoscopes, and portable video processors primarily to the aircraft engine manufacturing and aircraft engine maintenance industries. The company offers its products to the ENT doctors, urologists, gastroenterologists, primary care physicians, pulmonologists and other airway management doctors in hospitals, medical clinics, and physicians’ private offices. It provides its products through sales representatives in the United States; and through independent distributors in Europe, Asia, Australia, Canada, the Middle East, Africa, and Central and South America. The company was founded in 1987 and is based in Orangeburg, New York.

Vital Signs makes disposable medical products used to help patients breathe during surgery, in critical care settings, and to treat sleep disorders. Its anesthesia products include face masks and tubes, while its respiratory/critical care unit makes manual resuscitators, humidifiers, blood pressure cuffs, and other hospital products. Joint venture subsidiary Sleep Services of America diagnoses sleep disorders, such as obstructive sleep apnea (OSA), at more than 60 labs in seven states. In 2008 Vital Signs was acquired by GE Healthcare.

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