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Advocate Charitable Foundation is the faith-based philanthropic arm of Advocate Health Care. Advocate Charitable Foundation mission is to build relationships and partnerships across Chicago and to inspire charitable giving by individuals, foundations, corporations, and organizations. The not-for-profit group funds programs that offer patient care, research, education, and community-based health services. These include caregiver education classes, family-focused support groups, cancer research facilities, and specialized clinics throughout the city. Advocate Charitable Foundation began as Evangelical Health Foundation in 1984 and took its current name in 1995.

Africare helps Africans help themselves. The not-for-profit organization provides support to communities in Africa in areas such as health care, food security, agriculture, education, environmental management, and water resource development. Africare also works to help people create small business, such as growing sunflowers and pressing the seeds into cooking oil, and to provide emergency humanitarian aid when needed. Africare has given more than $675 million in aid to more than 35 countries in Africa, funding more than 2,000 projects. Africare HIV/AIDS Initiative works to raise awareness, promote safe sex, and increase access to health services. William and Barbara Kirker founded the organization in 1970.

Air Serv International transports relief supplies for humanitarian organizations. The nonprofit organization flies food, medicine, and other needed items to destinations all over the world that have been affected by wars or natural disasters, including Iraq, Afghanistan, and several countries in Africa. Air Serv International, Inc. fleet, based in various locations overseas, consists of several models of single- and twin-engine planes and helicopters, and it leases additional aircraft as needed. Support for the organization's efforts comes mainly from government grants and contracts. Air Serv International was founded in 1984. Air Serv International's Abeche Base in Eastern Chad provides a life line to the refugee camps along the Chad-Sudan border in support of the humanitarian response of the UN High Commissioner for Refugees (UNHCR) and implementing partners. The program is funded by the Department of State’s Bureau of Population, Refugees, and Migration (BPRM).

The Alaska Conservation Foundation strives to protect the environment (and all its inhabitants) in Alaska, as well as help the state's native people retain their cultural connections to the land. Alaska Conservation Foundation has awarded more than $22 million in grants to about 200 organizations. Alaska Conservation Foundation projects include the Alaska Coalition (national parks, wildlife refuges, and other federal lands), Alaska Oceans Program (conservation and sustainable fishing), Alaska Conservation for the Majority (finding common ground between conservationists and state residents), and Climate Change Program (minimizing individual impact). The Alaska Conservation Foundation was formed in 1980.

Alliance for Lupus Research was founded in 1999. The Alliance for Lupus Research (ALR) believes that the best way to combat systemic lupus erythematosus is through medical research on promising lupus treatment, cures, and prevention. The not-for-profit organization was formed to fund research into the prevention, treatment, and cure of systemic lupus erythematosus (lupus or SLE). Lupus is a sometimes fatal autoimmune disease that causes pain and stiffness in joints, ligaments, tendons, and bones as well as kidney, heart, lung, and liver problems. The ALR is the largest source of private funds for lupus research (including a project to map the genetic makeup of at-risk people and targeted treatments for lupus). Alliance for Lupus Research celebrated 10 years in existence in 2009.

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