Riteish Deshmukh is known for his work in Hindi and Marathi cinema.

Riteish is the son of the former Chief Minister of Maharashtra late Vilasrao Deshmukh and Vaishali Deshmukh.

Deshmukh debuted with K. Vijaya Bhaskar's Tujhe Meri Kasam (2003) opposite Genelia D'Souza.

Riteish Deshmukh has starred in many commercially successful films such as Kya Kool Hai Hum, Bluffmaster!, Malamaal Weekly, Heyy Babyy, Dhamaal, Housefull, Tere Naal Love Ho Gaya, Housefull 2, Grand Masti, Ek Villain, and Housefull 3.

In January 2013, Riteish made his debut as an film producer with the Marathi success Balak Palak, directed by Ravi Jadhav.

In 2013 , Riteish made his acting debut in Marathi cinema with the action film Lai Bhaari

Deshmukh launched his own production house Mumbai Film Company in 2013 with producing a Marathi film Balak Palak, which was a huge success and won several awards.

Riteish married Genelia D'Souza, his co-star from Tujhe Meri Kasam, Masti and Tere Naal Love Ho Gaya on 3 February 2012. Their first son, Riaan, was born on 24 November 2014. Their second son, Rahyl, was born on 1 June 2016.

The actor donated Rs 25 lakhs to his home town Latur for 'Jalyukta Latur', an initiative to make the parched district water sufficient.