He is also known for his works in British Indian films, Hollywood ventures, and a Telugu films.

He also hosted the TV show Mano Ya Na Mano and appeared in popular Vodafone commercials.

In 2012 he appeared in the title role in Paan Singh Tomar, a biopic about an athlete. Both the movie and Khan's performance received critical acclaim.

As of 2013, he had appeared in more than 30 films in Bollywood.

Khan has won three Filmfare Awards, a Screen Actors Guild Award, and an Independent Spirit Award nomination.

He is also the recipient of 2011 Padma Shri award, the fourth highest civilian award in India.

He has garnered the National Film Award for Best Actor in the 60th National Film Awards 2012, for his performance in Paan Singh Tomar.

Khan was studying for his MA degree when he earned a scholarship to study at National School of Drama (NSD) in New Delhi in 1984.

On 23 February 1995, Khan married writer Sutapa Sikdar, who is also an NSD graduate. They have two children named Babil and Aryan.

In 2014, Khan appeared in Gunday, which was a moderate box office success.